Frequency of cytokine gene promoter polymorphisms in the Northern Ireland Cystic Fibrosis population

Alison P. Watt, Owen A. Ross, Julia Courtney, Derek Middleton, Madeleine Ennis, J. Stuart Elborn

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

It has been postulated that cytokine allele frequencies are gender and perhaps geographically-specific. Cytokine release is crucial in the regulation of the type and magnitude of the immune response. This study observed no differences in the frequency of cytokine promoter polymorphisms associated with variant levels of expression in patients with CF and a non-CF population of Northern Ireland.

Original languageEnglish (US)
Pages (from-to)363-365
Number of pages3
JournalJournal of Cystic Fibrosis
Volume6
Issue number5
DOIs
StatePublished - Sep 2007

Keywords

  • Cystic Fibrosis
  • Cytokine
  • PCR
  • Polymorphism

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pulmonary and Respiratory Medicine

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