Frequency of cytokine gene promoter polymorphisms in the Northern Ireland Cystic Fibrosis population

Alison P. Watt; Owen A. Ross; Julia Courtney; Derek Middleton; Madeleine Ennis; J. Stuart Elborn

doi:10.1016/j.jcf.2007.01.002

Frequency of cytokine gene promoter polymorphisms in the Northern Ireland Cystic Fibrosis population

Alison P. Watt, Owen A. Ross, Julia Courtney, Derek Middleton, Madeleine Ennis, J. Stuart Elborn

Neuroscience

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

It has been postulated that cytokine allele frequencies are gender and perhaps geographically-specific. Cytokine release is crucial in the regulation of the type and magnitude of the immune response. This study observed no differences in the frequency of cytokine promoter polymorphisms associated with variant levels of expression in patients with CF and a non-CF population of Northern Ireland.

Original language	English (US)
Pages (from-to)	363-365
Number of pages	3
Journal	Journal of Cystic Fibrosis
Volume	6
Issue number	5
DOIs	https://doi.org/10.1016/j.jcf.2007.01.002
State	Published - Sep 2007

Keywords

Cystic Fibrosis
Cytokine
PCR
Polymorphism

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Pulmonary and Respiratory Medicine

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10.1016/j.jcf.2007.01.002

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title = "Frequency of cytokine gene promoter polymorphisms in the Northern Ireland Cystic Fibrosis population",

abstract = "It has been postulated that cytokine allele frequencies are gender and perhaps geographically-specific. Cytokine release is crucial in the regulation of the type and magnitude of the immune response. This study observed no differences in the frequency of cytokine promoter polymorphisms associated with variant levels of expression in patients with CF and a non-CF population of Northern Ireland.",

keywords = "Cystic Fibrosis, Cytokine, PCR, Polymorphism",

author = "Watt, {Alison P.} and Ross, {Owen A.} and Julia Courtney and Derek Middleton and Madeleine Ennis and Elborn, {J. Stuart}",

year = "2007",

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AU - Watt, Alison P.

AU - Ross, Owen A.

AU - Courtney, Julia

AU - Middleton, Derek

AU - Ennis, Madeleine

AU - Elborn, J. Stuart

PY - 2007/9

Y1 - 2007/9

N2 - It has been postulated that cytokine allele frequencies are gender and perhaps geographically-specific. Cytokine release is crucial in the regulation of the type and magnitude of the immune response. This study observed no differences in the frequency of cytokine promoter polymorphisms associated with variant levels of expression in patients with CF and a non-CF population of Northern Ireland.

AB - It has been postulated that cytokine allele frequencies are gender and perhaps geographically-specific. Cytokine release is crucial in the regulation of the type and magnitude of the immune response. This study observed no differences in the frequency of cytokine promoter polymorphisms associated with variant levels of expression in patients with CF and a non-CF population of Northern Ireland.

KW - Cystic Fibrosis

KW - Cytokine

KW - PCR

KW - Polymorphism

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ER -

Frequency of cytokine gene promoter polymorphisms in the Northern Ireland Cystic Fibrosis population

Abstract

Keywords

ASJC Scopus subject areas

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