Free fatty acid metabolism in the follicular and luteal phases of the menstrual cycle

Valarie J. Heiling, Michael Dennis Jensen

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

To determine whether the hormonal changes associated with the normal menstrual cycle influence FFA metabolism, FFA turnover was measured in 12 women during both the follicular (days 4-10) and luteal (days 18-24) phases of their menstrual cycles. The luteal phase was confirmed by increased serum progesterone concentrations. Overnight postabsorptive FFA flux was similar in the follicular and luteal phases of the menstrual cycle (6.9 ± 0.8 us. 5.8 ± 0.5 μmol kg-1 min-1, respectively, P = NS). In addition, the FFA response to 3 h of somatostatin-induced hypoinsulinemia was virtually identical on both study days. Finally, we compared the intraindividual variability of basal FFA flux from studies performed in different us. the same phase of the menstrual cycle; no difference was present. We conclude that the cyclic changes in estrogen and progesterone production which occur during the normal menstrual cycle appear to have minor, if any, effects on FFA mobilization.

Original languageEnglish (US)
Pages (from-to)806-810
Number of pages5
JournalJournal of Clinical Endocrinology and Metabolism
Volume74
Issue number4
StatePublished - Apr 1992

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Follicular Phase
Luteal Phase
Menstrual Cycle
Nonesterified Fatty Acids
Metabolism
Progesterone
Fluxes
Somatostatin
Estrogens
Corpus Luteum
Serum

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology, Diabetes and Metabolism

Cite this

Free fatty acid metabolism in the follicular and luteal phases of the menstrual cycle. / Heiling, Valarie J.; Jensen, Michael Dennis.

In: Journal of Clinical Endocrinology and Metabolism, Vol. 74, No. 4, 04.1992, p. 806-810.

Research output: Contribution to journalArticle

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