Fractures attributable to osteoporosis: Report from the national osteoporosis foundation

L. J. Melton, M. Thamer, N. F. Ray, J. K. Chan, C. H. Chesnut, T. A. Einhorn, C. C. Johnston, L. G. Raisz, S. L. Silverman, E. S. Siris

Research output: Contribution to journalArticle

424 Citations (Scopus)

Abstract

To assess the cost-effectiveness of interventions to prevent osteoporosis, it is necessary to estimate total health care expenditures for the treatment of osteoporotic fractures. Resources utilized for the treatment of many diseases can be estimated from secondary databases using relevant diagnosis codes, but such codes do not indicate which fractures are osteoporotic in nature. Therefore, a panel of experts was convened to make judgments about the probabilities that fractures of different types might be related to osteoporosis according to patient age, gender, and rare. A three- round Delphi process was applied to estimate the proportion of fractures related to osteoporosis (i.e., the osteoporosis attribution probabilities) in 72 categories comprised of four specific fracture types (hip, spine, forearm, all other sites combined) stratified by three age groups (45-64 years, 65-84 years, 85 years and older), three racial groups (white, black, all others), and both genders (female, male). It was estimated that at least 90% of all hip and spine fractures among elderly white women should be attributed to osteoporosis. Much smaller proportions of the other fractures were attributed to osteoporosis. Regardless of fracture type, attribution probabilities were less for men than women and generally less for non-whites than whites. These probabilities will be used to estimate the total direct medical costs associated with osteoporosis-related fractures in the United States.

Original languageEnglish (US)
Pages (from-to)16-23
Number of pages8
JournalJournal of Bone and Mineral Research
Volume12
Issue number1
DOIs
StatePublished - 1997
Externally publishedYes

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Osteoporosis
Osteoporotic Fractures
Hip Fractures
Spine
Health Expenditures
Forearm
Cost-Benefit Analysis
Age Groups
Databases
Delivery of Health Care
Costs and Cost Analysis
Therapeutics

ASJC Scopus subject areas

  • Surgery

Cite this

Melton, L. J., Thamer, M., Ray, N. F., Chan, J. K., Chesnut, C. H., Einhorn, T. A., ... Siris, E. S. (1997). Fractures attributable to osteoporosis: Report from the national osteoporosis foundation. Journal of Bone and Mineral Research, 12(1), 16-23. https://doi.org/10.1359/jbmr.1997.12.1.16

Fractures attributable to osteoporosis : Report from the national osteoporosis foundation. / Melton, L. J.; Thamer, M.; Ray, N. F.; Chan, J. K.; Chesnut, C. H.; Einhorn, T. A.; Johnston, C. C.; Raisz, L. G.; Silverman, S. L.; Siris, E. S.

In: Journal of Bone and Mineral Research, Vol. 12, No. 1, 1997, p. 16-23.

Research output: Contribution to journalArticle

Melton, LJ, Thamer, M, Ray, NF, Chan, JK, Chesnut, CH, Einhorn, TA, Johnston, CC, Raisz, LG, Silverman, SL & Siris, ES 1997, 'Fractures attributable to osteoporosis: Report from the national osteoporosis foundation', Journal of Bone and Mineral Research, vol. 12, no. 1, pp. 16-23. https://doi.org/10.1359/jbmr.1997.12.1.16
Melton, L. J. ; Thamer, M. ; Ray, N. F. ; Chan, J. K. ; Chesnut, C. H. ; Einhorn, T. A. ; Johnston, C. C. ; Raisz, L. G. ; Silverman, S. L. ; Siris, E. S. / Fractures attributable to osteoporosis : Report from the national osteoporosis foundation. In: Journal of Bone and Mineral Research. 1997 ; Vol. 12, No. 1. pp. 16-23.
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