Fracture risk in patients with Parkinsonism: A population-based study in Olmsted County, Minnesota

O. Johnell, L. J. Melton, E. J. Atkinson, W. M. O'Fallon, L. T. Kurland

Research output: Contribution to journalArticle

177 Scopus citations

Abstract

In this population-based retrospective cohort study the 138 Olmsted County Minnesota residents first diagnosed with Parkinson's disease during 1967-79 were matched by age and sex to an equal number of control subjects from the community. Fractures were assessed through review of each subject's complete (inpatient and outpatient) medical records. At the time of diagnosis, County residents with parkinsonism were no more likely to have a history of selected fractures than control subjects (32% in each group). Subsequently 33% of cases and 20% of controls experienced one or more new fractures during 696 person-years of follow-up (p = 0.008). The greatest increase in risk was seen for proximal femur fractures confirming previous case-control studies. By 10 years after diagnosis an estimated 27% of the parkinsonism cohort had experienced a new hip fracture. The pattern of fractures that was observed suggested that the increased risk was due more to specific types of falls than to disuse osteoporosis.

Original languageEnglish (US)
Pages (from-to)32-38
Number of pages7
JournalAge and Ageing
Volume21
Issue number1
StatePublished - 1992

ASJC Scopus subject areas

  • Aging
  • Geriatrics and Gerontology

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    Johnell, O., Melton, L. J., Atkinson, E. J., O'Fallon, W. M., & Kurland, L. T. (1992). Fracture risk in patients with Parkinsonism: A population-based study in Olmsted County, Minnesota. Age and Ageing, 21(1), 32-38.