Formation and stability of β-hairpin structures in polypeptides

Francisco Blanco, Marina Ramírez-Alvarado, Luis Serrano

Research output: Contribution to journalArticle

134 Scopus citations


Experimental work on peptide models with β-hairpin structures has provided new insights into the formation and stability of this secondary structure element. Both the turn region and the antiparallel strand residues not only affect the overall stability of the hairpin, but also determine the type of hairpin formed. These results agree reasonably well with those from experimental and statistical analyses of β-sheet structures in proteins.

Original languageEnglish (US)
Pages (from-to)107-111
Number of pages5
JournalCurrent Opinion in Structural Biology
Issue number1
StatePublished - Feb 1998


ASJC Scopus subject areas

  • Structural Biology
  • Molecular Biology

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