Formation and stability of β-hairpin structures in polypeptides

Francisco Blanco, Marina Ramirez-Alvarado, Luis Serrano

Research output: Contribution to journalArticle

134 Citations (Scopus)

Abstract

Experimental work on peptide models with β-hairpin structures has provided new insights into the formation and stability of this secondary structure element. Both the turn region and the antiparallel strand residues not only affect the overall stability of the hairpin, but also determine the type of hairpin formed. These results agree reasonably well with those from experimental and statistical analyses of β-sheet structures in proteins.

Original languageEnglish (US)
Pages (from-to)107-111
Number of pages5
JournalCurrent Opinion in Structural Biology
Volume8
Issue number1
DOIs
StatePublished - Feb 1998
Externally publishedYes

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Peptides
Proteins

ASJC Scopus subject areas

  • Molecular Biology
  • Structural Biology

Cite this

Formation and stability of β-hairpin structures in polypeptides. / Blanco, Francisco; Ramirez-Alvarado, Marina; Serrano, Luis.

In: Current Opinion in Structural Biology, Vol. 8, No. 1, 02.1998, p. 107-111.

Research output: Contribution to journalArticle

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