Food deprivation and feeding of broiler chickens is associated with rapid and interdependent changes in the somatotrophic and thyrotrophic axes

J. Buyse, E. Decuypere, V. M. Darras, L. M. Vleurick, E. R. Kühn, Johannes D Veldhuis

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

1. In several experiments, hormonal changes in the somatotrophic axis, growth hormone (GH) sensitivity to a GH-secretagogue, thyroid hormones and their metabolising enzymes and plasma glucose levels were measured in relation to food deprivation and reinitiation after a single daily meal in 4- to 5-week-old male broiler chickens. 2. Floor-reared male broiler chickens were fed ad libitum or were restricted to a daily food intake of 40 or 45 g per d from the age of 2 weeks onwards. The daily food allowance was consumed in 0.5 h. 3. Food deprivation increased plasma GH concentrations but decreased GH-dependent variables such as plasma insulin-like growth factor-I and 3,3′,5-triiodothyronine (T3) concentrations. Hepatic inner ring deiodinating type III activity was markedly elevated, presumably as a consequence of low hepatic GH receptor numbers, and is thought to be the causal mechanism for the low plasma T3 concentrations. Food intake reversed these variables in a time-related manner. 4. GH pulsatility characteristics, as calculated by deconvolution analysis, revealed profound changes between food restricted and ad libitum fed animals. Chickens deprived of food for about 23.5 h were characterised by an enhanced pulsatile GH release as reflected in the higher GH secretory burst amplitude, GH mass per burst, GH production rate and GH pulse frequency. These variables returned very quickly to normal values after refeeding. 5. In summary, these experiments taken together demonstrate very clearly the interdependent and time-related changes of the somatotrophic and thyroid axes upon a single meal in previously food-deprived broiler chickens.

Original languageEnglish (US)
Pages (from-to)107-116
Number of pages10
JournalBritish Poultry Science
Volume41
Issue number1
StatePublished - 2000
Externally publishedYes

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Food Deprivation
food deprivation
somatotropin
Growth Hormone
Chickens
broiler chickens
triiodothyronine
Food
Meals
food intake
Eating
Somatotropin Receptors
liver
refeeding
Liver
Triiodothyronine
thyroid hormones
insulin-like growth factor I
Insulin-Like Growth Factor I
Thyroid Hormones

ASJC Scopus subject areas

  • Animal Science and Zoology

Cite this

Buyse, J., Decuypere, E., Darras, V. M., Vleurick, L. M., Kühn, E. R., & Veldhuis, J. D. (2000). Food deprivation and feeding of broiler chickens is associated with rapid and interdependent changes in the somatotrophic and thyrotrophic axes. British Poultry Science, 41(1), 107-116.

Food deprivation and feeding of broiler chickens is associated with rapid and interdependent changes in the somatotrophic and thyrotrophic axes. / Buyse, J.; Decuypere, E.; Darras, V. M.; Vleurick, L. M.; Kühn, E. R.; Veldhuis, Johannes D.

In: British Poultry Science, Vol. 41, No. 1, 2000, p. 107-116.

Research output: Contribution to journalArticle

Buyse, J, Decuypere, E, Darras, VM, Vleurick, LM, Kühn, ER & Veldhuis, JD 2000, 'Food deprivation and feeding of broiler chickens is associated with rapid and interdependent changes in the somatotrophic and thyrotrophic axes', British Poultry Science, vol. 41, no. 1, pp. 107-116.
Buyse, J. ; Decuypere, E. ; Darras, V. M. ; Vleurick, L. M. ; Kühn, E. R. ; Veldhuis, Johannes D. / Food deprivation and feeding of broiler chickens is associated with rapid and interdependent changes in the somatotrophic and thyrotrophic axes. In: British Poultry Science. 2000 ; Vol. 41, No. 1. pp. 107-116.
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