Follicular bronchitis/bronchiolitis

Samuel A. Yousem, Thomas V. Colby, Charles B. Carrington

Research output: Contribution to journalArticle

173 Citations (Scopus)

Abstract

Nineteen open lung biopsies demonstrating follicular bronchitis/bronchiolitis were reviewed with special attention to clinical manifestations. Morphologically, follicular bronchitis/bronchiolitis was represented by coalescent reactive germinal centers adjacent to airways in the absence of clinical or pathologic evidence of chronic obstructive pulmonary disease or bronchiectasis. Three clinicopathologic groups were identified: 1) patients with collagen vascular diseases, especially rheumatoid arthritis and Sjögren's syndrome; 2) patients with a familial form of the disease or with immunodeficiency syndromes; and 3) a heterogeneous group of patients with frequent peripheral blood eosinophilia, suggesting a hypersensitivity reaction. Prognosis was related to age at the time of biopsy and, to some extent, to the clinical group. Steroid therapy had inconsistent effects in all groups identified. The differential diagnosis of lymphoid lesions in the lung is also discussed.

Original languageEnglish (US)
Pages (from-to)700-706
Number of pages7
JournalHuman Pathology
Volume16
Issue number7
DOIs
StatePublished - 1985
Externally publishedYes

Fingerprint

Bronchiolitis
Bronchitis
Biopsy
Collagen Diseases
Lung
Bronchiectasis
Germinal Center
Eosinophilia
Vascular Diseases
Chronic Obstructive Pulmonary Disease
Rheumatoid Arthritis
Hypersensitivity
Differential Diagnosis
Steroids
Therapeutics

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Yousem, S. A., Colby, T. V., & Carrington, C. B. (1985). Follicular bronchitis/bronchiolitis. Human Pathology, 16(7), 700-706. https://doi.org/10.1016/S0046-8177(85)80155-6

Follicular bronchitis/bronchiolitis. / Yousem, Samuel A.; Colby, Thomas V.; Carrington, Charles B.

In: Human Pathology, Vol. 16, No. 7, 1985, p. 700-706.

Research output: Contribution to journalArticle

Yousem, SA, Colby, TV & Carrington, CB 1985, 'Follicular bronchitis/bronchiolitis', Human Pathology, vol. 16, no. 7, pp. 700-706. https://doi.org/10.1016/S0046-8177(85)80155-6
Yousem, Samuel A. ; Colby, Thomas V. ; Carrington, Charles B. / Follicular bronchitis/bronchiolitis. In: Human Pathology. 1985 ; Vol. 16, No. 7. pp. 700-706.
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