Focal Cerebral Ischemia: Pathophysiologic Mechanisms and Rationale for Future Avenues of Treatment

FREDRIC B. MEYER, THORALF M. SUNDT, TAKEHIKO YANAGIHARA, ROBERT E. ANDERSON

Research output: Contribution to journalReview article

56 Scopus citations

Abstract

Although approximately 500,000 patients suffer from a stroke each year in the United States, treatment of these patients to date has consisted primarily of prevention, supportive measures, and rehabilitation. The modification of experimental cerebral infarction by new pharmacologic agents, along with encouraging results from the restoration of blood flow to areas of focal ischemia in both laboratory and clinical trials, suggests that a more aggressive approach might be considered in selected patients with acute stroke.

Original languageEnglish (US)
Pages (from-to)35-55
Number of pages21
JournalMayo Clinic proceedings
Volume62
Issue number1
DOIs
StatePublished - Jan 1 1987

ASJC Scopus subject areas

  • Medicine(all)

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    MEYER, FREDRIC. B., SUNDT, THORALF. M., YANAGIHARA, TAKEHIKO., & ANDERSON, ROBERT. E. (1987). Focal Cerebral Ischemia: Pathophysiologic Mechanisms and Rationale for Future Avenues of Treatment. Mayo Clinic proceedings, 62(1), 35-55. https://doi.org/10.1016/S0025-6196(12)61523-7