Abstract
Flushing, urticaria, and angioedema are clinical findings that are commonly associated with anaphylaxis. Flushing can be quite dramatic but is less common in anaphylaxis than are urticaria and angioedema, symptoms that are commonly mentioned together as a single symptom,urticaria/angioedema. Differentiation of dry flushing, due to circulating agents acting directly on smooth muscle, from wet flushing, due to neurogenic triggers from the shared autonomic innervation of blood vessels and sweat glands, can be helpful in sorting out causes of flushing. Flushing may be idiopathic, but may also occur in conditions such as carcinoid syndrome (CS), mastocytosis, mast cell activation disorder (MCAD), pheochromocytoma, medullary carcinoma of the thyroid (MCT), icthyotoxicosis, and other conditions with symptoms that overlap those of anaphylaxis. Chronic urticaria can exist as an independent syndrome that does not commonly have anaphylactic features or signs. However, urticaria can also occur as one of the symptoms of an anaphylactic response. Cholinergic urticaria and cold urticaria are the two physical urticarias that are associated with anaphylaxis.
| Original language | English (US) |
|---|---|
| Title of host publication | Anaphylaxis and Hypersensitivity Reactions |
| Publisher | Humana Press |
| Pages | 271-284 |
| Number of pages | 14 |
| ISBN (Print) | 9781603279505 |
| DOIs | |
| State | Published - 2011 |
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Keywords
- Anaphylaxis
- Angioedema
- Blush distribution
- Carcinoid syndrome
- Cholinergic urticaria
- Cold urticaria
- Flushing
- Icthyotoxicosis
- Mast cell activation disorder
- Mastocytosis
- Medullary carcinoma of the thyroid
- Pheochromocytoma
- Physical urticarias
- Prostaglandin D2
- Spells
- Urticaria
ASJC Scopus subject areas
- Medicine(all)
Cite this
Flushing and urticarial syndromes presenting as anaphylaxis. / Butterfield, Joseph H.
Anaphylaxis and Hypersensitivity Reactions. Humana Press, 2011. p. 271-284.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Flushing and urticarial syndromes presenting as anaphylaxis
AU - Butterfield, Joseph H.
PY - 2011
Y1 - 2011
N2 - Flushing, urticaria, and angioedema are clinical findings that are commonly associated with anaphylaxis. Flushing can be quite dramatic but is less common in anaphylaxis than are urticaria and angioedema, symptoms that are commonly mentioned together as a single symptom,urticaria/angioedema. Differentiation of dry flushing, due to circulating agents acting directly on smooth muscle, from wet flushing, due to neurogenic triggers from the shared autonomic innervation of blood vessels and sweat glands, can be helpful in sorting out causes of flushing. Flushing may be idiopathic, but may also occur in conditions such as carcinoid syndrome (CS), mastocytosis, mast cell activation disorder (MCAD), pheochromocytoma, medullary carcinoma of the thyroid (MCT), icthyotoxicosis, and other conditions with symptoms that overlap those of anaphylaxis. Chronic urticaria can exist as an independent syndrome that does not commonly have anaphylactic features or signs. However, urticaria can also occur as one of the symptoms of an anaphylactic response. Cholinergic urticaria and cold urticaria are the two physical urticarias that are associated with anaphylaxis.
AB - Flushing, urticaria, and angioedema are clinical findings that are commonly associated with anaphylaxis. Flushing can be quite dramatic but is less common in anaphylaxis than are urticaria and angioedema, symptoms that are commonly mentioned together as a single symptom,urticaria/angioedema. Differentiation of dry flushing, due to circulating agents acting directly on smooth muscle, from wet flushing, due to neurogenic triggers from the shared autonomic innervation of blood vessels and sweat glands, can be helpful in sorting out causes of flushing. Flushing may be idiopathic, but may also occur in conditions such as carcinoid syndrome (CS), mastocytosis, mast cell activation disorder (MCAD), pheochromocytoma, medullary carcinoma of the thyroid (MCT), icthyotoxicosis, and other conditions with symptoms that overlap those of anaphylaxis. Chronic urticaria can exist as an independent syndrome that does not commonly have anaphylactic features or signs. However, urticaria can also occur as one of the symptoms of an anaphylactic response. Cholinergic urticaria and cold urticaria are the two physical urticarias that are associated with anaphylaxis.
KW - Anaphylaxis
KW - Angioedema
KW - Blush distribution
KW - Carcinoid syndrome
KW - Cholinergic urticaria
KW - Cold urticaria
KW - Flushing
KW - Icthyotoxicosis
KW - Mast cell activation disorder
KW - Mastocytosis
KW - Medullary carcinoma of the thyroid
KW - Pheochromocytoma
KW - Physical urticarias
KW - Prostaglandin D2
KW - Spells
KW - Urticaria
UR - http://www.scopus.com/inward/record.url?scp=84885736802&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84885736802&partnerID=8YFLogxK
U2 - 10.1007/978-1-60327-951-2_17
DO - 10.1007/978-1-60327-951-2_17
M3 - Chapter
AN - SCOPUS:84885736802
SN - 9781603279505
SP - 271
EP - 284
BT - Anaphylaxis and Hypersensitivity Reactions
PB - Humana Press
ER -