Fluorodeoxyglucose F18 positron emission tomography in a case of slowly progressive pure alexia

Jonathan Graff-Radford, Eduardo E. Benarroch, Joseph R. Duffy, Daniel A. Drubach

Research output: Contribution to journalArticle

Abstract

We describe a 71-year-old patient with slowly progressive pure alexia in which analysis of her fluorodeoxyglucose FDG-PET scan revealed an area of focal hypometabolism in the visual word form area. She presented with difficulty reading. Examination revealed pure alexia with preservation of other cognitive domains. Brain MRI revealed only slight atrophy. A Fluorodeoxyglucose F18 positron emission tomography scan revealed hypometabolism in the occipital cortex bilaterally, left greater than right, with normal metabolism elsewhere in the brain. This case highlights the utility of FDG-PET scan in evaluating focal neurodegenerative conditions before clear atrophy can be seen on MRI.

Original languageEnglish (US)
Pages (from-to)476-479
Number of pages4
JournalNeurocase
Volume20
Issue number4
DOIs
StatePublished - Jul 2014

Keywords

  • Alexia
  • Dementia
  • Fluorodeoxyglucose F18 positron emission tomography

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology

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