Fluorodeoxyglucose F18 positron emission tomography in a case of slowly progressive pure alexia

Jonathan Graff-Radford; Eduardo E. Benarroch; Joseph R. Duffy; Daniel A. Drubach

doi:10.1080/13554794.2013.826677

Fluorodeoxyglucose F18 positron emission tomography in a case of slowly progressive pure alexia

Jonathan Graff-Radford, Eduardo E. Benarroch, Joseph R. Duffy, Daniel A. Drubach

Neurology

Research output: Contribution to journal › Article › peer-review

Abstract

We describe a 71-year-old patient with slowly progressive pure alexia in which analysis of her fluorodeoxyglucose FDG-PET scan revealed an area of focal hypometabolism in the visual word form area. She presented with difficulty reading. Examination revealed pure alexia with preservation of other cognitive domains. Brain MRI revealed only slight atrophy. A Fluorodeoxyglucose F18 positron emission tomography scan revealed hypometabolism in the occipital cortex bilaterally, left greater than right, with normal metabolism elsewhere in the brain. This case highlights the utility of FDG-PET scan in evaluating focal neurodegenerative conditions before clear atrophy can be seen on MRI.

Original language	English (US)
Pages (from-to)	476-479
Number of pages	4
Journal	Neurocase
Volume	20
Issue number	4
DOIs	https://doi.org/10.1080/13554794.2013.826677
State	Published - Jul 2014

Keywords

Alexia
Dementia
Fluorodeoxyglucose F18 positron emission tomography

ASJC Scopus subject areas

Arts and Humanities (miscellaneous)
Clinical Neurology

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10.1080/13554794.2013.826677

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AB - We describe a 71-year-old patient with slowly progressive pure alexia in which analysis of her fluorodeoxyglucose FDG-PET scan revealed an area of focal hypometabolism in the visual word form area. She presented with difficulty reading. Examination revealed pure alexia with preservation of other cognitive domains. Brain MRI revealed only slight atrophy. A Fluorodeoxyglucose F18 positron emission tomography scan revealed hypometabolism in the occipital cortex bilaterally, left greater than right, with normal metabolism elsewhere in the brain. This case highlights the utility of FDG-PET scan in evaluating focal neurodegenerative conditions before clear atrophy can be seen on MRI.

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Fluorodeoxyglucose F18 positron emission tomography in a case of slowly progressive pure alexia

Abstract

Keywords

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