Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome

Colin K. Grissom, Eliotte L. Hirshberg, Justin B. Dickerson, Samuel M. Brown, Michael J. Lanspa, Kathleen D. Liu, David Schoenfeld, Mark Tidswell, R. Duncan Hite, Peter Rock, Russell R. Miller, Alan H. Morris, L. Hudson, S. Gundel, C. Hough, M. Neff, K. Sims, A. Ungar, T. Watkins, J. SteingrubM. Tidswell, E. Braden, L. DeSouza, J. Germain, C. Kardos, D. Kelley, L. Kozikowski, S. Ouellette, K. Guntupalli, V. Bandi, C. Pope, C. Ross, R. Brower, H. Fessler, D. Hager, P. Mendez-Tellez, D. Needham, K. Oakjones, J. Sevransky, A. Workneh, C. Shanholtz, D. Herr, H. Howes, G. Netzer, P. Rock, A. Sampaio, J. Titus, P. Sloane, T. Beck, H. Highfield, S. King, B. Lee, N. Bolouri, H. P. Wiedemann, R. W. Ashton, D. A. Culver, T. Frederick, J. A. Guzman, J. J. Komara, A. J. Reddy, R. Hejal, M. Andrews, D. Haney, A. F. Connors, S. Lasalvia, J. D. Thornton, E. L. Warren, M. Moss, E. L. Burnham, L. Gray, J. Maloney, M. Mealer, I. Douglas, K. Overdier, K. Thompson, R. Wolken, S. Frankel, J. McKeehan, M. L. Warner, T. Bost, C. Higgins, K. Hodgin, N. MacIntyre, L. Brown, C. Cox, M. Gentile, J. Govert, N. Knudsen, S. Carson, L. Chang, S. Choudhury, W. Hall, J. Lanier, A. P. Wheeler, G. R. Bernard, M. Hays, S. Mogan, T. Rice, R. D. Hite, K. Bender, A. Harvey, P. E. Morris, Mary Ragusky, P. Wright, S. Groce, J. McLean, A. Overton, J. Truwit, K. Enfield, M. Marshall, A. Morris, A. Austin, S. Barney, S. Brown, J. Ferguson, H. Gallo, T. Graydon, C. Grissom, E. Hirshberg, A. Jephson, N. Kumar, R. Miller, D. Murphy, J. Orme, A. Stowe, L. Struck, F. Thomas, D. Ward, L. Weaver, P. Bailey, W. Beninati, L. Bezdijan, T. Clemmer, S. Rimkus, R. Tanaka, C. Lawton, D. Hanselman, K. Sundar, W. Alward, C. Bishop, D. Eckley, T. Hill, B. Jensen, K. Ludwig, D. Nielsen, M. Pearce, M. A. Matthay, C. Calfee, B. Daniel, M. Eisner, O. Garcia, K. Kordesch, K. Liu, N. Shum, H. Zhou, M. W. Peterson, J. Blaauw, K. Van Gundy, T. Albertson, B. Morrissey, E. Vlastelin, R. Hubmayr, D. Brown, M. Dubin, Emir Festic, Ognjen Gajic, R. Hinds, S. Holets, Daryl J Kor, A. Lee, M. Passe, G. Simpson, J. Wright, B. DeBoisblanc, A. Antoine, D. Charbonnet, J. Hunt, P. Lauto, A. Marr, G. Meyaski, C. Romaine, R. Tejedor, S. Brierre, J. Byrne, T. Jagneaux, C. LeBlanc, K. Moreau, C. Thomas, S. Jain, D. Taylor, L. Seoane, C. Hebert, J. Thompson, F. Simeone, J. Fearon, D. Schoenfeld, M. Guha, E. Hammond, N. Lavery, P. Lazar, R. Morse, C. Oldmixon, N. Ringwood, E. Smoot, B. T. Thompson, R. Wilson, A. Harabin, S. Bredow, M. Waclawiw, G. Weinmann

Research output: Contribution to journal › Article

47 Citations (Scopus)

Abstract

Objectives: In the Fluid and Catheter Treatment Trial (FACTT) of the National Institutes of Health Acute Respiratory Distress Syndrome Network, a conservative fluid protocol (FACTT Conservative) resulted in a lower cumulative fluid balance and better outcomes than a liberal fluid protocol (FACTT Liberal). Subsequent Acute Respiratory Distress Syndrome Network studies used a simplified conservative fluid protocol (FACTT Lite). The objective of this study was to compare the performance of FACTT Lite, FACTT Conservative, and FACTT Liberal protocols.

Original languageEnglish (US)
Pages (from-to)288-295
Number of pages8
JournalCritical Care Medicine
Volume43
Issue number2
DOIs
StatePublished - Feb 1 2015

Fingerprint

Adult Respiratory Distress Syndrome
Catheters
Therapeutics
Water-Electrolyte Balance
National Institutes of Health (U.S.)
Clinical Protocols

Keywords

  • Acute kidney injury
  • Adult respiratory distress syndrome
  • Clinical protocols
  • Critical illness
  • Fluid therapy
  • Shock

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine
  • Medicine(all)

Cite this

Grissom, C. K., Hirshberg, E. L., Dickerson, J. B., Brown, S. M., Lanspa, M. J., Liu, K. D., ... Weinmann, G. (2015). Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome. Critical Care Medicine, 43(2), 288-295. https://doi.org/10.1097/CCM.0000000000000715

Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome. / Grissom, Colin K.; Hirshberg, Eliotte L.; Dickerson, Justin B.; Brown, Samuel M.; Lanspa, Michael J.; Liu, Kathleen D.; Schoenfeld, David; Tidswell, Mark; Hite, R. Duncan; Rock, Peter; Miller, Russell R.; Morris, Alan H.; Hudson, L.; Gundel, S.; Hough, C.; Neff, M.; Sims, K.; Ungar, A.; Watkins, T.; Steingrub, J.; Tidswell, M.; Braden, E.; DeSouza, L.; Germain, J.; Kardos, C.; Kelley, D.; Kozikowski, L.; Ouellette, S.; Guntupalli, K.; Bandi, V.; Pope, C.; Ross, C.; Brower, R.; Fessler, H.; Hager, D.; Mendez-Tellez, P.; Needham, D.; Oakjones, K.; Sevransky, J.; Workneh, A.; Shanholtz, C.; Herr, D.; Howes, H.; Netzer, G.; Rock, P.; Sampaio, A.; Titus, J.; Sloane, P.; Beck, T.; Highfield, H.; King, S.; Lee, B.; Bolouri, N.; Wiedemann, H. P.; Ashton, R. W.; Culver, D. A.; Frederick, T.; Guzman, J. A.; Komara, J. J.; Reddy, A. J.; Hejal, R.; Andrews, M.; Haney, D.; Connors, A. F.; Lasalvia, S.; Thornton, J. D.; Warren, E. L.; Moss, M.; Burnham, E. L.; Gray, L.; Maloney, J.; Mealer, M.; Douglas, I.; Overdier, K.; Thompson, K.; Wolken, R.; Frankel, S.; McKeehan, J.; Warner, M. L.; Bost, T.; Higgins, C.; Hodgin, K.; MacIntyre, N.; Brown, L.; Cox, C.; Gentile, M.; Govert, J.; Knudsen, N.; Carson, S.; Chang, L.; Choudhury, S.; Hall, W.; Lanier, J.; Wheeler, A. P.; Bernard, G. R.; Hays, M.; Mogan, S.; Rice, T.; Hite, R. D.; Bender, K.; Harvey, A.; Morris, P. E.; Ragusky, Mary; Wright, P.; Groce, S.; McLean, J.; Overton, A.; Truwit, J.; Enfield, K.; Marshall, M.; Morris, A.; Austin, A.; Barney, S.; Brown, S.; Ferguson, J.; Gallo, H.; Graydon, T.; Grissom, C.; Hirshberg, E.; Jephson, A.; Kumar, N.; Miller, R.; Murphy, D.; Orme, J.; Stowe, A.; Struck, L.; Thomas, F.; Ward, D.; Weaver, L.; Bailey, P.; Beninati, W.; Bezdijan, L.; Clemmer, T.; Rimkus, S.; Tanaka, R.; Lawton, C.; Hanselman, D.; Sundar, K.; Alward, W.; Bishop, C.; Eckley, D.; Hill, T.; Jensen, B.; Ludwig, K.; Nielsen, D.; Pearce, M.; Matthay, M. A.; Calfee, C.; Daniel, B.; Eisner, M.; Garcia, O.; Kordesch, K.; Liu, K.; Shum, N.; Zhou, H.; Peterson, M. W.; Blaauw, J.; Van Gundy, K.; Albertson, T.; Morrissey, B.; Vlastelin, E.; Hubmayr, R.; Brown, D.; Dubin, M.; Festic, Emir; Gajic, Ognjen; Hinds, R.; Holets, S.; Kor, Daryl J; Lee, A.; Passe, M.; Simpson, G.; Wright, J.; DeBoisblanc, B.; Antoine, A.; Charbonnet, D.; Hunt, J.; Lauto, P.; Marr, A.; Meyaski, G.; Romaine, C.; Tejedor, R.; Brierre, S.; Byrne, J.; Jagneaux, T.; LeBlanc, C.; Moreau, K.; Thomas, C.; Jain, S.; Taylor, D.; Seoane, L.; Hebert, C.; Thompson, J.; Simeone, F.; Fearon, J.; Schoenfeld, D.; Guha, M.; Hammond, E.; Lavery, N.; Lazar, P.; Morse, R.; Oldmixon, C.; Ringwood, N.; Smoot, E.; Thompson, B. T.; Wilson, R.; Harabin, A.; Bredow, S.; Waclawiw, M.; Weinmann, G.

In: Critical Care Medicine, Vol. 43, No. 2, 01.02.2015, p. 288-295.

Research output: Contribution to journal › Article

Grissom, CK, Hirshberg, EL, Dickerson, JB, Brown, SM, Lanspa, MJ, Liu, KD, Schoenfeld, D, Tidswell, M, Hite, RD, Rock, P, Miller, RR, Morris, AH, Hudson, L, Gundel, S, Hough, C, Neff, M, Sims, K, Ungar, A, Watkins, T, Steingrub, J, Tidswell, M, Braden, E, DeSouza, L, Germain, J, Kardos, C, Kelley, D, Kozikowski, L, Ouellette, S, Guntupalli, K, Bandi, V, Pope, C, Ross, C, Brower, R, Fessler, H, Hager, D, Mendez-Tellez, P, Needham, D, Oakjones, K, Sevransky, J, Workneh, A, Shanholtz, C, Herr, D, Howes, H, Netzer, G, Rock, P, Sampaio, A, Titus, J, Sloane, P, Beck, T, Highfield, H, King, S, Lee, B, Bolouri, N, Wiedemann, HP, Ashton, RW, Culver, DA, Frederick, T, Guzman, JA, Komara, JJ, Reddy, AJ, Hejal, R, Andrews, M, Haney, D, Connors, AF, Lasalvia, S, Thornton, JD, Warren, EL, Moss, M, Burnham, EL, Gray, L, Maloney, J, Mealer, M, Douglas, I, Overdier, K, Thompson, K, Wolken, R, Frankel, S, McKeehan, J, Warner, ML, Bost, T, Higgins, C, Hodgin, K, MacIntyre, N, Brown, L, Cox, C, Gentile, M, Govert, J, Knudsen, N, Carson, S, Chang, L, Choudhury, S, Hall, W, Lanier, J, Wheeler, AP, Bernard, GR, Hays, M, Mogan, S, Rice, T, Hite, RD, Bender, K, Harvey, A, Morris, PE, Ragusky, M, Wright, P, Groce, S, McLean, J, Overton, A, Truwit, J, Enfield, K, Marshall, M, Morris, A, Austin, A, Barney, S, Brown, S, Ferguson, J, Gallo, H, Graydon, T, Grissom, C, Hirshberg, E, Jephson, A, Kumar, N, Miller, R, Murphy, D, Orme, J, Stowe, A, Struck, L, Thomas, F, Ward, D, Weaver, L, Bailey, P, Beninati, W, Bezdijan, L, Clemmer, T, Rimkus, S, Tanaka, R, Lawton, C, Hanselman, D, Sundar, K, Alward, W, Bishop, C, Eckley, D, Hill, T, Jensen, B, Ludwig, K, Nielsen, D, Pearce, M, Matthay, MA, Calfee, C, Daniel, B, Eisner, M, Garcia, O, Kordesch, K, Liu, K, Shum, N, Zhou, H, Peterson, MW, Blaauw, J, Van Gundy, K, Albertson, T, Morrissey, B, Vlastelin, E, Hubmayr, R, Brown, D, Dubin, M, Festic, E, Gajic, O, Hinds, R, Holets, S, Kor, DJ, Lee, A, Passe, M, Simpson, G, Wright, J, DeBoisblanc, B, Antoine, A, Charbonnet, D, Hunt, J, Lauto, P, Marr, A, Meyaski, G, Romaine, C, Tejedor, R, Brierre, S, Byrne, J, Jagneaux, T, LeBlanc, C, Moreau, K, Thomas, C, Jain, S, Taylor, D, Seoane, L, Hebert, C, Thompson, J, Simeone, F, Fearon, J, Schoenfeld, D, Guha, M, Hammond, E, Lavery, N, Lazar, P, Morse, R, Oldmixon, C, Ringwood, N, Smoot, E, Thompson, BT, Wilson, R, Harabin, A, Bredow, S, Waclawiw, M & Weinmann, G 2015, 'Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome', Critical Care Medicine, vol. 43, no. 2, pp. 288-295. https://doi.org/10.1097/CCM.0000000000000715
Grissom CK, Hirshberg EL, Dickerson JB, Brown SM, Lanspa MJ, Liu KD et al. Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome. Critical Care Medicine. 2015 Feb 1;43(2):288-295. https://doi.org/10.1097/CCM.0000000000000715
Grissom, Colin K. ; Hirshberg, Eliotte L. ; Dickerson, Justin B. ; Brown, Samuel M. ; Lanspa, Michael J. ; Liu, Kathleen D. ; Schoenfeld, David ; Tidswell, Mark ; Hite, R. Duncan ; Rock, Peter ; Miller, Russell R. ; Morris, Alan H. ; Hudson, L. ; Gundel, S. ; Hough, C. ; Neff, M. ; Sims, K. ; Ungar, A. ; Watkins, T. ; Steingrub, J. ; Tidswell, M. ; Braden, E. ; DeSouza, L. ; Germain, J. ; Kardos, C. ; Kelley, D. ; Kozikowski, L. ; Ouellette, S. ; Guntupalli, K. ; Bandi, V. ; Pope, C. ; Ross, C. ; Brower, R. ; Fessler, H. ; Hager, D. ; Mendez-Tellez, P. ; Needham, D. ; Oakjones, K. ; Sevransky, J. ; Workneh, A. ; Shanholtz, C. ; Herr, D. ; Howes, H. ; Netzer, G. ; Rock, P. ; Sampaio, A. ; Titus, J. ; Sloane, P. ; Beck, T. ; Highfield, H. ; King, S. ; Lee, B. ; Bolouri, N. ; Wiedemann, H. P. ; Ashton, R. W. ; Culver, D. A. ; Frederick, T. ; Guzman, J. A. ; Komara, J. J. ; Reddy, A. J. ; Hejal, R. ; Andrews, M. ; Haney, D. ; Connors, A. F. ; Lasalvia, S. ; Thornton, J. D. ; Warren, E. L. ; Moss, M. ; Burnham, E. L. ; Gray, L. ; Maloney, J. ; Mealer, M. ; Douglas, I. ; Overdier, K. ; Thompson, K. ; Wolken, R. ; Frankel, S. ; McKeehan, J. ; Warner, M. L. ; Bost, T. ; Higgins, C. ; Hodgin, K. ; MacIntyre, N. ; Brown, L. ; Cox, C. ; Gentile, M. ; Govert, J. ; Knudsen, N. ; Carson, S. ; Chang, L. ; Choudhury, S. ; Hall, W. ; Lanier, J. ; Wheeler, A. P. ; Bernard, G. R. ; Hays, M. ; Mogan, S. ; Rice, T. ; Hite, R. D. ; Bender, K. ; Harvey, A. ; Morris, P. E. ; Ragusky, Mary ; Wright, P. ; Groce, S. ; McLean, J. ; Overton, A. ; Truwit, J. ; Enfield, K. ; Marshall, M. ; Morris, A. ; Austin, A. ; Barney, S. ; Brown, S. ; Ferguson, J. ; Gallo, H. ; Graydon, T. ; Grissom, C. ; Hirshberg, E. ; Jephson, A. ; Kumar, N. ; Miller, R. ; Murphy, D. ; Orme, J. ; Stowe, A. ; Struck, L. ; Thomas, F. ; Ward, D. ; Weaver, L. ; Bailey, P. ; Beninati, W. ; Bezdijan, L. ; Clemmer, T. ; Rimkus, S. ; Tanaka, R. ; Lawton, C. ; Hanselman, D. ; Sundar, K. ; Alward, W. ; Bishop, C. ; Eckley, D. ; Hill, T. ; Jensen, B. ; Ludwig, K. ; Nielsen, D. ; Pearce, M. ; Matthay, M. A. ; Calfee, C. ; Daniel, B. ; Eisner, M. ; Garcia, O. ; Kordesch, K. ; Liu, K. ; Shum, N. ; Zhou, H. ; Peterson, M. W. ; Blaauw, J. ; Van Gundy, K. ; Albertson, T. ; Morrissey, B. ; Vlastelin, E. ; Hubmayr, R. ; Brown, D. ; Dubin, M. ; Festic, Emir ; Gajic, Ognjen ; Hinds, R. ; Holets, S. ; Kor, Daryl J ; Lee, A. ; Passe, M. ; Simpson, G. ; Wright, J. ; DeBoisblanc, B. ; Antoine, A. ; Charbonnet, D. ; Hunt, J. ; Lauto, P. ; Marr, A. ; Meyaski, G. ; Romaine, C. ; Tejedor, R. ; Brierre, S. ; Byrne, J. ; Jagneaux, T. ; LeBlanc, C. ; Moreau, K. ; Thomas, C. ; Jain, S. ; Taylor, D. ; Seoane, L. ; Hebert, C. ; Thompson, J. ; Simeone, F. ; Fearon, J. ; Schoenfeld, D. ; Guha, M. ; Hammond, E. ; Lavery, N. ; Lazar, P. ; Morse, R. ; Oldmixon, C. ; Ringwood, N. ; Smoot, E. ; Thompson, B. T. ; Wilson, R. ; Harabin, A. ; Bredow, S. ; Waclawiw, M. ; Weinmann, G. / Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome. In: Critical Care Medicine. 2015 ; Vol. 43, No. 2. pp. 288-295.
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title = "Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome",
abstract = "Objectives: In the Fluid and Catheter Treatment Trial (FACTT) of the National Institutes of Health Acute Respiratory Distress Syndrome Network, a conservative fluid protocol (FACTT Conservative) resulted in a lower cumulative fluid balance and better outcomes than a liberal fluid protocol (FACTT Liberal). Subsequent Acute Respiratory Distress Syndrome Network studies used a simplified conservative fluid protocol (FACTT Lite). The objective of this study was to compare the performance of FACTT Lite, FACTT Conservative, and FACTT Liberal protocols.",
keywords = "Acute kidney injury, Adult respiratory distress syndrome, Clinical protocols, Critical illness, Fluid therapy, Shock",
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TY - JOUR

T1 - Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome

AU - Grissom, Colin K.

AU - Hirshberg, Eliotte L.

AU - Dickerson, Justin B.

AU - Brown, Samuel M.

AU - Lanspa, Michael J.

AU - Liu, Kathleen D.

AU - Schoenfeld, David

AU - Tidswell, Mark

AU - Hite, R. Duncan

AU - Rock, Peter

AU - Miller, Russell R.

AU - Morris, Alan H.

AU - Hudson, L.

AU - Gundel, S.

AU - Hough, C.

AU - Neff, M.

AU - Sims, K.

AU - Ungar, A.

AU - Watkins, T.

AU - Steingrub, J.

AU - Tidswell, M.

AU - Braden, E.

AU - DeSouza, L.

AU - Germain, J.

AU - Kardos, C.

AU - Kelley, D.

AU - Kozikowski, L.

AU - Ouellette, S.

AU - Guntupalli, K.

AU - Bandi, V.

AU - Pope, C.

AU - Ross, C.

AU - Brower, R.

AU - Fessler, H.

AU - Hager, D.

AU - Mendez-Tellez, P.

AU - Needham, D.

AU - Oakjones, K.

AU - Sevransky, J.

AU - Workneh, A.

AU - Shanholtz, C.

AU - Herr, D.

AU - Howes, H.

AU - Netzer, G.

AU - Rock, P.

AU - Sampaio, A.

AU - Titus, J.

AU - Sloane, P.

AU - Beck, T.

AU - Highfield, H.

AU - King, S.

AU - Lee, B.

AU - Bolouri, N.

AU - Wiedemann, H. P.

AU - Ashton, R. W.

AU - Culver, D. A.

AU - Frederick, T.

AU - Guzman, J. A.

AU - Komara, J. J.

AU - Reddy, A. J.

AU - Hejal, R.

AU - Andrews, M.

AU - Haney, D.

AU - Connors, A. F.

AU - Lasalvia, S.

AU - Thornton, J. D.

AU - Warren, E. L.

AU - Moss, M.

AU - Burnham, E. L.

AU - Gray, L.

AU - Maloney, J.

AU - Mealer, M.

AU - Douglas, I.

AU - Overdier, K.

AU - Thompson, K.

AU - Wolken, R.

AU - Frankel, S.

AU - McKeehan, J.

AU - Warner, M. L.

AU - Bost, T.

AU - Higgins, C.

AU - Hodgin, K.

AU - MacIntyre, N.

AU - Brown, L.

AU - Cox, C.

AU - Gentile, M.

AU - Govert, J.

AU - Knudsen, N.

AU - Carson, S.

AU - Chang, L.

AU - Choudhury, S.

AU - Hall, W.

AU - Lanier, J.

AU - Wheeler, A. P.

AU - Bernard, G. R.

AU - Hays, M.

AU - Mogan, S.

AU - Rice, T.

AU - Hite, R. D.

AU - Bender, K.

AU - Harvey, A.

AU - Morris, P. E.

AU - Ragusky, Mary

AU - Wright, P.

AU - Groce, S.

AU - McLean, J.

AU - Overton, A.

AU - Truwit, J.

AU - Enfield, K.

AU - Marshall, M.

AU - Morris, A.

AU - Austin, A.

AU - Barney, S.

AU - Brown, S.

AU - Ferguson, J.

AU - Gallo, H.

AU - Graydon, T.

AU - Grissom, C.

AU - Hirshberg, E.

AU - Jephson, A.

AU - Kumar, N.

AU - Miller, R.

AU - Murphy, D.

AU - Orme, J.

AU - Stowe, A.

AU - Struck, L.

AU - Thomas, F.

AU - Ward, D.

AU - Weaver, L.

AU - Bailey, P.

AU - Beninati, W.

AU - Bezdijan, L.

AU - Clemmer, T.

AU - Rimkus, S.

AU - Tanaka, R.

AU - Lawton, C.

AU - Hanselman, D.

AU - Sundar, K.

AU - Alward, W.

AU - Bishop, C.

AU - Eckley, D.

AU - Hill, T.

AU - Jensen, B.

AU - Ludwig, K.

AU - Nielsen, D.

AU - Pearce, M.

AU - Matthay, M. A.

AU - Calfee, C.

AU - Daniel, B.

AU - Eisner, M.

AU - Garcia, O.

AU - Kordesch, K.

AU - Liu, K.

AU - Shum, N.

AU - Zhou, H.

AU - Peterson, M. W.

AU - Blaauw, J.

AU - Van Gundy, K.

AU - Albertson, T.

AU - Morrissey, B.

AU - Vlastelin, E.

AU - Hubmayr, R.

AU - Brown, D.

AU - Dubin, M.

AU - Festic, Emir

AU - Gajic, Ognjen

AU - Hinds, R.

AU - Holets, S.

AU - Kor, Daryl J

AU - Lee, A.

AU - Passe, M.

AU - Simpson, G.

AU - Wright, J.

AU - DeBoisblanc, B.

AU - Antoine, A.

AU - Charbonnet, D.

AU - Hunt, J.

AU - Lauto, P.

AU - Marr, A.

AU - Meyaski, G.

AU - Romaine, C.

AU - Tejedor, R.

AU - Brierre, S.

AU - Byrne, J.

AU - Jagneaux, T.

AU - LeBlanc, C.

AU - Moreau, K.

AU - Thomas, C.

AU - Jain, S.

AU - Taylor, D.

AU - Seoane, L.

AU - Hebert, C.

AU - Thompson, J.

AU - Simeone, F.

AU - Fearon, J.

AU - Schoenfeld, D.

AU - Guha, M.

AU - Hammond, E.

AU - Lavery, N.

AU - Lazar, P.

AU - Morse, R.

AU - Oldmixon, C.

AU - Ringwood, N.

AU - Smoot, E.

AU - Thompson, B. T.

AU - Wilson, R.

AU - Harabin, A.

AU - Bredow, S.

AU - Waclawiw, M.

AU - Weinmann, G.

PY - 2015/2/1

Y1 - 2015/2/1

N2 - Objectives: In the Fluid and Catheter Treatment Trial (FACTT) of the National Institutes of Health Acute Respiratory Distress Syndrome Network, a conservative fluid protocol (FACTT Conservative) resulted in a lower cumulative fluid balance and better outcomes than a liberal fluid protocol (FACTT Liberal). Subsequent Acute Respiratory Distress Syndrome Network studies used a simplified conservative fluid protocol (FACTT Lite). The objective of this study was to compare the performance of FACTT Lite, FACTT Conservative, and FACTT Liberal protocols.

AB - Objectives: In the Fluid and Catheter Treatment Trial (FACTT) of the National Institutes of Health Acute Respiratory Distress Syndrome Network, a conservative fluid protocol (FACTT Conservative) resulted in a lower cumulative fluid balance and better outcomes than a liberal fluid protocol (FACTT Liberal). Subsequent Acute Respiratory Distress Syndrome Network studies used a simplified conservative fluid protocol (FACTT Lite). The objective of this study was to compare the performance of FACTT Lite, FACTT Conservative, and FACTT Liberal protocols.

KW - Acute kidney injury

KW - Adult respiratory distress syndrome

KW - Clinical protocols

KW - Critical illness

KW - Fluid therapy

KW - Shock

UR - http://www.scopus.com/inward/record.url?scp=84925294058&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84925294058&partnerID=8YFLogxK

U2 - 10.1097/CCM.0000000000000715

DO - 10.1097/CCM.0000000000000715

M3 - Article

C2 - 25599463

AN - SCOPUS:84925294058

VL - 43

SP - 288

EP - 295

JO - Critical Care Medicine

JF - Critical Care Medicine

SN - 0090-3493

IS - 2

ER -

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