Flavones and sesquiterpene lactones from Achillea atrata subsp, multifida: Antimicrobial activity

Ivana Aljančić; Vlatka Vajs; Nebojša Menković; Ivanka Karadžić; Nenad Juranić; Slobodan Milosavljević; Slobodan Macura

doi:10.1021/np980536m

Flavones and sesquiterpene lactones from Achillea atrata subsp, multifida: Antimicrobial activity

Ivana Aljančić, Vlatka Vajs, Nebojša Menković, Ivanka Karadžić, Nenad Juranić, Slobodan Milosavljević, Slobodan Macura

Biochemistry and Molecular Biology

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Abstract

Four flavones (1-4) and nine sesquiterpene lactones (5-13), one of them (5) a new compound, were isolated from the aerial parts of Achillea atrata L. subsp, multifida. Although the crude extract demonstrated in vitro inhibitory activity against Candida albicans and Bacillus subtilis, all isolated flavones were active against B. subtilis. Flavones 1, 2, and 3 were also active against C. albicans, while 1 and 3 exhibited activity against E. coli, as well. None of the tested lactones (7, 9, 12, and 13) showed any antimicrobial activity.

Original language	English (US)
Pages (from-to)	909-911
Number of pages	3
Journal	Journal of Natural Products
Volume	62
Issue number	6
DOIs	https://doi.org/10.1021/np980536m
State	Published - Jun 1999

ASJC Scopus subject areas

Analytical Chemistry
Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine
Organic Chemistry

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10.1021/np980536m

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abstract = "Four flavones (1-4) and nine sesquiterpene lactones (5-13), one of them (5) a new compound, were isolated from the aerial parts of Achillea atrata L. subsp, multifida. Although the crude extract demonstrated in vitro inhibitory activity against Candida albicans and Bacillus subtilis, all isolated flavones were active against B. subtilis. Flavones 1, 2, and 3 were also active against C. albicans, while 1 and 3 exhibited activity against E. coli, as well. None of the tested lactones (7, 9, 12, and 13) showed any antimicrobial activity.",

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T1 - Flavones and sesquiterpene lactones from Achillea atrata subsp, multifida

T2 - Antimicrobial activity

AU - Aljančić, Ivana

AU - Vajs, Vlatka

AU - Menković, Nebojša

AU - Karadžić, Ivanka

AU - Juranić, Nenad

AU - Milosavljević, Slobodan

AU - Macura, Slobodan

PY - 1999/6

Y1 - 1999/6

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Flavones and sesquiterpene lactones from Achillea atrata subsp, multifida: Antimicrobial activity

Abstract

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