FKBP5 as a selection biomarker for gemcitabine and AKT inhibitors in treatment of pancreatic cancer

Medicine & Life Sciences

• gemcitabine 69%
• triciribine 68%
• Pancreatic Neoplasms 58%
• Heterografts 55%
• Biomarkers 40%
• Immunophilins 19%
• Neoplasms 15%
• Cell Line 14%
• Phosphatidylinositol 3-Kinases 12%
• Therapeutics 10%
• Down-Regulation 8%
• Phosphorylation 8%
• Clinical Trials 8%
• Staining and Labeling 7%
• Drug Therapy 7%
• Growth 6%
• In Vitro Techniques 5%
• Pharmaceutical Preparations 5%
• Proteins 4%

Agriculture & Biology

• pancreatic neoplasms 100%
• biomarkers 56%
• neoplasms 47%
• mice 35%
• cell lines 23%
• scaffolding proteins 21%
• phosphatidylinositol 3-kinase 20%
• dephosphorylation 18%
• clinical trials 16%
• drug therapy 15%
• animal models 13%
• phosphorylation 13%
• therapeutics 12%
• staining 11%
• drugs 10%
• tissues 6%
• cells 4%

Chemical Compounds

• Triciribine 97%
• Gemcitabine 92%
• Protein Kinase B Inhibitor 55%
• Biological Marker 55%
• Sensitization 33%
• Mammalian Target of Rapamycin Inhibitor 26%
• Dephosphorylation 19%
• Antineoplastic Agent 13%
• Resistance 9%
• Drug 8%
• Protein 6%