Five cases of fulminant hepatitis due to herpes simplex virus in adults

Antonio D. Pinna, Jorge Rakela, Anthony J. Demetris, John J. Fung

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

Five cases of fulminant hepatitis due to herpes simplex virus were identified among patients admitted to the Thomas E. Starzl Transplantation Institute between January 1991 and September 1994. The diagnosis was established in three of the five patients on the basis of transjugular liver biopsy specimen results. These three patients were treated with acyclovir; two survived and one required liver transplantation. Early histologic diagnosis, specific antiviral treatment, and liver transplantation in selected patients may improve the clinical outcome of this almost uniformly fatal disease.

Original languageEnglish (US)
Pages (from-to)750-754
Number of pages5
JournalDigestive Diseases and Sciences
Volume47
Issue number4
DOIs
StatePublished - 2002
Externally publishedYes

Fingerprint

Simplexvirus
Hepatitis
Liver Transplantation
Acyclovir
Antiviral Agents
Early Diagnosis
Transplantation
Biopsy
Liver
Therapeutics

Keywords

  • Hepatitis
  • Herpes simplex virus
  • Transplantation

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Five cases of fulminant hepatitis due to herpes simplex virus in adults. / Pinna, Antonio D.; Rakela, Jorge; Demetris, Anthony J.; Fung, John J.

In: Digestive Diseases and Sciences, Vol. 47, No. 4, 2002, p. 750-754.

Research output: Contribution to journalArticle

Pinna, Antonio D. ; Rakela, Jorge ; Demetris, Anthony J. ; Fung, John J. / Five cases of fulminant hepatitis due to herpes simplex virus in adults. In: Digestive Diseases and Sciences. 2002 ; Vol. 47, No. 4. pp. 750-754.
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