TY - JOUR
T1 - Fibrous dysplasia of the skull base
AU - Lynch, James J.
AU - Duke, Derek A.
AU - Meyer, Fredric B.
AU - Unni, K. K.
PY - 1998
Y1 - 1998
N2 - This study examined the presentation, surgical complications, and outcome associated with treating 82 cases of skull base fibrous dysplasia (SBFD). Eighty-two cases of SBFD were identified. All pathology was reviewed by a senior pathologist (K. Unni). The medical records were reviewed for presenting symptoms, treatment, surgical complications, outcome, and follow-up. Fifty-one males (62)% and 31 females (38%), mean age 24 years, were operated on. Distributed in frontal 72%, ethmoid 61%, sphenoid 57%, fronto-ethmoid-sphenoidal 39%, frontoethmoidal 38%, temporal 12%, and occipital 12% locations. Orbit involved in 66%. Patients presented with facial asymmetry 61%, proptosis 41%, headache 39%, and visual loss 15%. Gross total resection was achieved in 51%, and subtotal 49%. Complications included anosmia 13%, visual worsening 11%, infection 10%, ocular paresis 4%, CSF leak 2.5%. One patient spontaneously progressed to fibrosarcoma. Mean follow-up was 11 years (range 0-55) Twenty-two percent had progression of residual FD (4% symptomatic).
AB - This study examined the presentation, surgical complications, and outcome associated with treating 82 cases of skull base fibrous dysplasia (SBFD). Eighty-two cases of SBFD were identified. All pathology was reviewed by a senior pathologist (K. Unni). The medical records were reviewed for presenting symptoms, treatment, surgical complications, outcome, and follow-up. Fifty-one males (62)% and 31 females (38%), mean age 24 years, were operated on. Distributed in frontal 72%, ethmoid 61%, sphenoid 57%, fronto-ethmoid-sphenoidal 39%, frontoethmoidal 38%, temporal 12%, and occipital 12% locations. Orbit involved in 66%. Patients presented with facial asymmetry 61%, proptosis 41%, headache 39%, and visual loss 15%. Gross total resection was achieved in 51%, and subtotal 49%. Complications included anosmia 13%, visual worsening 11%, infection 10%, ocular paresis 4%, CSF leak 2.5%. One patient spontaneously progressed to fibrosarcoma. Mean follow-up was 11 years (range 0-55) Twenty-two percent had progression of residual FD (4% symptomatic).
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M3 - Article
AN - SCOPUS:33747805907
SN - 1052-1453
VL - 8
SP - 25
JO - Skull Base Surgery
JF - Skull Base Surgery
IS - SUPPL. 1
ER -