Fibrous dysplasia of the skull base

James J. Lynch, Derek A. Duke, Fredric B. Meyer, K. K. Unni

Research output: Contribution to journalArticle

Abstract

This study examined the presentation, surgical complications, and outcome associated with treating 82 cases of skull base fibrous dysplasia (SBFD). Eighty-two cases of SBFD were identified. All pathology was reviewed by a senior pathologist (K. Unni). The medical records were reviewed for presenting symptoms, treatment, surgical complications, outcome, and follow-up. Fifty-one males (62)% and 31 females (38%), mean age 24 years, were operated on. Distributed in frontal 72%, ethmoid 61%, sphenoid 57%, fronto-ethmoid-sphenoidal 39%, frontoethmoidal 38%, temporal 12%, and occipital 12% locations. Orbit involved in 66%. Patients presented with facial asymmetry 61%, proptosis 41%, headache 39%, and visual loss 15%. Gross total resection was achieved in 51%, and subtotal 49%. Complications included anosmia 13%, visual worsening 11%, infection 10%, ocular paresis 4%, CSF leak 2.5%. One patient spontaneously progressed to fibrosarcoma. Mean follow-up was 11 years (range 0-55) Twenty-two percent had progression of residual FD (4% symptomatic).

Original languageEnglish (US)
Pages (from-to)25
Number of pages1
JournalSkull Base Surgery
Volume8
Issue numberSUPPL. 1
StatePublished - 1998
Externally publishedYes

Fingerprint

Skull Base
Facial Asymmetry
Olfaction Disorders
Eye Infections
Exophthalmos
Fibrosarcoma
Orbit
Paresis
Medical Records
Headache
Pathology
Therapeutics
Pathologists

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Lynch, J. J., Duke, D. A., Meyer, F. B., & Unni, K. K. (1998). Fibrous dysplasia of the skull base. Skull Base Surgery, 8(SUPPL. 1), 25.

Fibrous dysplasia of the skull base. / Lynch, James J.; Duke, Derek A.; Meyer, Fredric B.; Unni, K. K.

In: Skull Base Surgery, Vol. 8, No. SUPPL. 1, 1998, p. 25.

Research output: Contribution to journalArticle

Lynch, JJ, Duke, DA, Meyer, FB & Unni, KK 1998, 'Fibrous dysplasia of the skull base', Skull Base Surgery, vol. 8, no. SUPPL. 1, pp. 25.
Lynch JJ, Duke DA, Meyer FB, Unni KK. Fibrous dysplasia of the skull base. Skull Base Surgery. 1998;8(SUPPL. 1):25.
Lynch, James J. ; Duke, Derek A. ; Meyer, Fredric B. ; Unni, K. K. / Fibrous dysplasia of the skull base. In: Skull Base Surgery. 1998 ; Vol. 8, No. SUPPL. 1. pp. 25.
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