Feline immunodeficiency virus (FIV)-based lentiviral vectors are useful for introducing integrated transgenes into nondividing human cells. This article describes the production and use of advanced generation FIV vectors. Key properties are discussed in comparison to other lentiviral vectors. Additional topics include the practical implications of species-specific retroviral restriction factors and the production of nonintegrating FIV vectors.
|Original language||English (US)|
|Number of pages||6|
|Journal||Cold Spring Harbor Protocols|
|State||Published - Jan 2012|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)