Feasibility and application of 3-dimensional ultrasound for measurement of gastric volumes in healthy adults and adolescents

Mhd Louai Manini, Duane D. Burton, Duane D. Meixner, Deborah J. Eckert, Matthew Callstrom, Grant Schmit, Mounif El-Youssef, Michael Camilleri

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

OBJECTIVES: Abnormal gastric accommodation to a meal results in dyspepsia. Current methods to measure gastric volume (GV) are invasive or involve ionizing radiation. The aims of this study were to compare fasting and postprandial (PP) GVs measured by Tc-single photon emission computed tomography (SPECT) and 3-dimensional ultrasound (3D-US) in adults, to assess the performance characteristics of 3D-US measurement of GV during fasting and postprandially, and to develop normative data of GVs in 24 healthy adolescents. PATIENTS AND METHODS: Eleven adults underwent SPECT and 3D-US simultaneously to measure GV, and a second 3D-US alone within 1 week of the first study. Twenty-four adolescents underwent 1 3D-US measurement. Each study included fasting, a 300-mL Ensure meal, and 0 to 30-minute PP GV measurements. RESULTS: 3D-US identifies GV accommodation to 300 mL Ensure. Delta (0-30 minutes average PP fasting) GV was 444 mL (median, interquartile range [IQR] = 422, 534) for 3D-US and 543 mL (median, IQR = 486, 564) for SPECT (P = 0.15). There were larger interindividual coefficients of variation for GV by 3D-US (60.3% fasting and 21.3% average PP) compared with 19% fasting and 9.2% PP for SPECT. Intraindividual coefficients of variation for the 2 3D-US measurements in adults were 84% fasting and 44% average PP. The estimated GVs for the adolescent group (median [25th-75th IQR]) were 33 (18-53) mL fasting, 330 (284-357) mL 30 minutes PP, and 281 (240-324) mL for delta GV. CONCLUSIONS: 3D-US is a promising method to measure GV accommodation to a meal. Large coefficients of variation reflect the learning stage in development of this promising technique.

Original languageEnglish (US)
Pages (from-to)287-293
Number of pages7
JournalJournal of pediatric gastroenterology and nutrition
Volume48
Issue number3
DOIs
StatePublished - Mar 2009

Keywords

  • 3-Dimensional ultrasound
  • Gastric accommodation
  • Single photon emission computed tomography

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Gastroenterology

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