Feasibility and application of 3-dimensional ultrasound for measurement of gastric volumes in healthy adults and adolescents

Mhd Louai Manini, Duane D. Burton, Duane D. Meixner, Deborah J. Eckert, Matthew R Callstrom, Grant Schmit, Mounif El-Youssef, Michael Camilleri

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

OBJECTIVES: Abnormal gastric accommodation to a meal results in dyspepsia. Current methods to measure gastric volume (GV) are invasive or involve ionizing radiation. The aims of this study were to compare fasting and postprandial (PP) GVs measured by Tc-single photon emission computed tomography (SPECT) and 3-dimensional ultrasound (3D-US) in adults, to assess the performance characteristics of 3D-US measurement of GV during fasting and postprandially, and to develop normative data of GVs in 24 healthy adolescents. PATIENTS AND METHODS: Eleven adults underwent SPECT and 3D-US simultaneously to measure GV, and a second 3D-US alone within 1 week of the first study. Twenty-four adolescents underwent 1 3D-US measurement. Each study included fasting, a 300-mL Ensure meal, and 0 to 30-minute PP GV measurements. RESULTS: 3D-US identifies GV accommodation to 300 mL Ensure. Delta (0-30 minutes average PP fasting) GV was 444 mL (median, interquartile range [IQR] = 422, 534) for 3D-US and 543 mL (median, IQR = 486, 564) for SPECT (P = 0.15). There were larger interindividual coefficients of variation for GV by 3D-US (60.3% fasting and 21.3% average PP) compared with 19% fasting and 9.2% PP for SPECT. Intraindividual coefficients of variation for the 2 3D-US measurements in adults were 84% fasting and 44% average PP. The estimated GVs for the adolescent group (median [25th-75th IQR]) were 33 (18-53) mL fasting, 330 (284-357) mL 30 minutes PP, and 281 (240-324) mL for delta GV. CONCLUSIONS: 3D-US is a promising method to measure GV accommodation to a meal. Large coefficients of variation reflect the learning stage in development of this promising technique.

Original languageEnglish (US)
Pages (from-to)287-293
Number of pages7
JournalJournal of Pediatric Gastroenterology and Nutrition
Volume48
Issue number3
DOIs
StatePublished - Mar 2009

Fingerprint

Stomach
Fasting
Single-Photon Emission-Computed Tomography
Meals
Dyspepsia
Ionizing Radiation
Learning

Keywords

  • 3-Dimensional ultrasound
  • Gastric accommodation
  • Single photon emission computed tomography

ASJC Scopus subject areas

  • Gastroenterology
  • Pediatrics, Perinatology, and Child Health

Cite this

Feasibility and application of 3-dimensional ultrasound for measurement of gastric volumes in healthy adults and adolescents. / Manini, Mhd Louai; Burton, Duane D.; Meixner, Duane D.; Eckert, Deborah J.; Callstrom, Matthew R; Schmit, Grant; El-Youssef, Mounif; Camilleri, Michael.

In: Journal of Pediatric Gastroenterology and Nutrition, Vol. 48, No. 3, 03.2009, p. 287-293.

Research output: Contribution to journalArticle

Manini, Mhd Louai ; Burton, Duane D. ; Meixner, Duane D. ; Eckert, Deborah J. ; Callstrom, Matthew R ; Schmit, Grant ; El-Youssef, Mounif ; Camilleri, Michael. / Feasibility and application of 3-dimensional ultrasound for measurement of gastric volumes in healthy adults and adolescents. In: Journal of Pediatric Gastroenterology and Nutrition. 2009 ; Vol. 48, No. 3. pp. 287-293.
@article{10922a010174487191a963f81f517d5e,
title = "Feasibility and application of 3-dimensional ultrasound for measurement of gastric volumes in healthy adults and adolescents",
abstract = "OBJECTIVES: Abnormal gastric accommodation to a meal results in dyspepsia. Current methods to measure gastric volume (GV) are invasive or involve ionizing radiation. The aims of this study were to compare fasting and postprandial (PP) GVs measured by Tc-single photon emission computed tomography (SPECT) and 3-dimensional ultrasound (3D-US) in adults, to assess the performance characteristics of 3D-US measurement of GV during fasting and postprandially, and to develop normative data of GVs in 24 healthy adolescents. PATIENTS AND METHODS: Eleven adults underwent SPECT and 3D-US simultaneously to measure GV, and a second 3D-US alone within 1 week of the first study. Twenty-four adolescents underwent 1 3D-US measurement. Each study included fasting, a 300-mL Ensure meal, and 0 to 30-minute PP GV measurements. RESULTS: 3D-US identifies GV accommodation to 300 mL Ensure. Delta (0-30 minutes average PP fasting) GV was 444 mL (median, interquartile range [IQR] = 422, 534) for 3D-US and 543 mL (median, IQR = 486, 564) for SPECT (P = 0.15). There were larger interindividual coefficients of variation for GV by 3D-US (60.3{\%} fasting and 21.3{\%} average PP) compared with 19{\%} fasting and 9.2{\%} PP for SPECT. Intraindividual coefficients of variation for the 2 3D-US measurements in adults were 84{\%} fasting and 44{\%} average PP. The estimated GVs for the adolescent group (median [25th-75th IQR]) were 33 (18-53) mL fasting, 330 (284-357) mL 30 minutes PP, and 281 (240-324) mL for delta GV. CONCLUSIONS: 3D-US is a promising method to measure GV accommodation to a meal. Large coefficients of variation reflect the learning stage in development of this promising technique.",
keywords = "3-Dimensional ultrasound, Gastric accommodation, Single photon emission computed tomography",
author = "Manini, {Mhd Louai} and Burton, {Duane D.} and Meixner, {Duane D.} and Eckert, {Deborah J.} and Callstrom, {Matthew R} and Grant Schmit and Mounif El-Youssef and Michael Camilleri",
year = "2009",
month = "3",
doi = "10.1097/MPG.0b013e318189694f",
language = "English (US)",
volume = "48",
pages = "287--293",
journal = "Journal of Pediatric Gastroenterology and Nutrition",
issn = "0277-2116",
publisher = "Lippincott Williams and Wilkins",
number = "3",

}

TY - JOUR

T1 - Feasibility and application of 3-dimensional ultrasound for measurement of gastric volumes in healthy adults and adolescents

AU - Manini, Mhd Louai

AU - Burton, Duane D.

AU - Meixner, Duane D.

AU - Eckert, Deborah J.

AU - Callstrom, Matthew R

AU - Schmit, Grant

AU - El-Youssef, Mounif

AU - Camilleri, Michael

PY - 2009/3

Y1 - 2009/3

N2 - OBJECTIVES: Abnormal gastric accommodation to a meal results in dyspepsia. Current methods to measure gastric volume (GV) are invasive or involve ionizing radiation. The aims of this study were to compare fasting and postprandial (PP) GVs measured by Tc-single photon emission computed tomography (SPECT) and 3-dimensional ultrasound (3D-US) in adults, to assess the performance characteristics of 3D-US measurement of GV during fasting and postprandially, and to develop normative data of GVs in 24 healthy adolescents. PATIENTS AND METHODS: Eleven adults underwent SPECT and 3D-US simultaneously to measure GV, and a second 3D-US alone within 1 week of the first study. Twenty-four adolescents underwent 1 3D-US measurement. Each study included fasting, a 300-mL Ensure meal, and 0 to 30-minute PP GV measurements. RESULTS: 3D-US identifies GV accommodation to 300 mL Ensure. Delta (0-30 minutes average PP fasting) GV was 444 mL (median, interquartile range [IQR] = 422, 534) for 3D-US and 543 mL (median, IQR = 486, 564) for SPECT (P = 0.15). There were larger interindividual coefficients of variation for GV by 3D-US (60.3% fasting and 21.3% average PP) compared with 19% fasting and 9.2% PP for SPECT. Intraindividual coefficients of variation for the 2 3D-US measurements in adults were 84% fasting and 44% average PP. The estimated GVs for the adolescent group (median [25th-75th IQR]) were 33 (18-53) mL fasting, 330 (284-357) mL 30 minutes PP, and 281 (240-324) mL for delta GV. CONCLUSIONS: 3D-US is a promising method to measure GV accommodation to a meal. Large coefficients of variation reflect the learning stage in development of this promising technique.

AB - OBJECTIVES: Abnormal gastric accommodation to a meal results in dyspepsia. Current methods to measure gastric volume (GV) are invasive or involve ionizing radiation. The aims of this study were to compare fasting and postprandial (PP) GVs measured by Tc-single photon emission computed tomography (SPECT) and 3-dimensional ultrasound (3D-US) in adults, to assess the performance characteristics of 3D-US measurement of GV during fasting and postprandially, and to develop normative data of GVs in 24 healthy adolescents. PATIENTS AND METHODS: Eleven adults underwent SPECT and 3D-US simultaneously to measure GV, and a second 3D-US alone within 1 week of the first study. Twenty-four adolescents underwent 1 3D-US measurement. Each study included fasting, a 300-mL Ensure meal, and 0 to 30-minute PP GV measurements. RESULTS: 3D-US identifies GV accommodation to 300 mL Ensure. Delta (0-30 minutes average PP fasting) GV was 444 mL (median, interquartile range [IQR] = 422, 534) for 3D-US and 543 mL (median, IQR = 486, 564) for SPECT (P = 0.15). There were larger interindividual coefficients of variation for GV by 3D-US (60.3% fasting and 21.3% average PP) compared with 19% fasting and 9.2% PP for SPECT. Intraindividual coefficients of variation for the 2 3D-US measurements in adults were 84% fasting and 44% average PP. The estimated GVs for the adolescent group (median [25th-75th IQR]) were 33 (18-53) mL fasting, 330 (284-357) mL 30 minutes PP, and 281 (240-324) mL for delta GV. CONCLUSIONS: 3D-US is a promising method to measure GV accommodation to a meal. Large coefficients of variation reflect the learning stage in development of this promising technique.

KW - 3-Dimensional ultrasound

KW - Gastric accommodation

KW - Single photon emission computed tomography

UR - http://www.scopus.com/inward/record.url?scp=67649946973&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=67649946973&partnerID=8YFLogxK

U2 - 10.1097/MPG.0b013e318189694f

DO - 10.1097/MPG.0b013e318189694f

M3 - Article

C2 - 19274782

AN - SCOPUS:67649946973

VL - 48

SP - 287

EP - 293

JO - Journal of Pediatric Gastroenterology and Nutrition

JF - Journal of Pediatric Gastroenterology and Nutrition

SN - 0277-2116

IS - 3

ER -