Fatal hemoptysis from Behcet's disease in a child

Stephen D. Cohle, Thomas Colby

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Objective: To present a case of pulmonary artery aneurysms (PAAs) in a child with Behcet's disease (BD). Nature of the study: Case report and review of the literature. Materials and methods: The patient had a complete autopsy, drug screen and serological testing. A medical history was obtained and the literature was reviewed. Results: A 10-year-old African-American boy had massive hemoptysis while at home and died shortly thereafter in the emergency department of a local hospital. He had had two other episodes of hemoptysis in the past 2 months. At autopsy, he had bilateral inflammatory aneurysms of the lower lobe branches of the pulmonary arteries. The left aneurysm had eroded into the adjacent bronchus and accounted for the fatal hemoptysis. The right ventricle had endocardial fibrosis. Systemic vasculitis was absent. The child did not have oral, genital, eye or skin lesions at autopsy, or by clinical history. Based on the autopsy findings, a diagnosis of BD was made. Conclusions: We present the very unusual case of a 10-year-old African-American boy who died from hemoptysis resulting from bilateral pulmonary aneurysms caused by BD.

Original languageEnglish (US)
Pages (from-to)296-299
Number of pages4
JournalCardiovascular Pathology
Volume11
Issue number5
DOIs
StatePublished - Sep 2002

Fingerprint

Hemoptysis
Behcet Syndrome
Aneurysm
Autopsy
African Americans
Pulmonary Artery
Systemic Vasculitis
antineoplaston A10
Bronchi
Heart Ventricles
Hospital Emergency Service
Fibrosis
Lung
Skin
Pharmaceutical Preparations

Keywords

  • Behcet's disease
  • Death-sudden
  • Hughes-Stovin syndrome
  • Pulmonary arteritis
  • Pulmonary hemorrhage

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pathology and Forensic Medicine

Cite this

Fatal hemoptysis from Behcet's disease in a child. / Cohle, Stephen D.; Colby, Thomas.

In: Cardiovascular Pathology, Vol. 11, No. 5, 09.2002, p. 296-299.

Research output: Contribution to journalArticle

Cohle, Stephen D. ; Colby, Thomas. / Fatal hemoptysis from Behcet's disease in a child. In: Cardiovascular Pathology. 2002 ; Vol. 11, No. 5. pp. 296-299.
@article{c37fef0ad4714968b4f845fe2de538d4,
title = "Fatal hemoptysis from Behcet's disease in a child",
abstract = "Objective: To present a case of pulmonary artery aneurysms (PAAs) in a child with Behcet's disease (BD). Nature of the study: Case report and review of the literature. Materials and methods: The patient had a complete autopsy, drug screen and serological testing. A medical history was obtained and the literature was reviewed. Results: A 10-year-old African-American boy had massive hemoptysis while at home and died shortly thereafter in the emergency department of a local hospital. He had had two other episodes of hemoptysis in the past 2 months. At autopsy, he had bilateral inflammatory aneurysms of the lower lobe branches of the pulmonary arteries. The left aneurysm had eroded into the adjacent bronchus and accounted for the fatal hemoptysis. The right ventricle had endocardial fibrosis. Systemic vasculitis was absent. The child did not have oral, genital, eye or skin lesions at autopsy, or by clinical history. Based on the autopsy findings, a diagnosis of BD was made. Conclusions: We present the very unusual case of a 10-year-old African-American boy who died from hemoptysis resulting from bilateral pulmonary aneurysms caused by BD.",
keywords = "Behcet's disease, Death-sudden, Hughes-Stovin syndrome, Pulmonary arteritis, Pulmonary hemorrhage",
author = "Cohle, {Stephen D.} and Thomas Colby",
year = "2002",
month = "9",
doi = "10.1016/S1054-8807(02)00117-5",
language = "English (US)",
volume = "11",
pages = "296--299",
journal = "Cardiovascular Pathology",
issn = "1054-8807",
publisher = "Elsevier Inc.",
number = "5",

}

TY - JOUR

T1 - Fatal hemoptysis from Behcet's disease in a child

AU - Cohle, Stephen D.

AU - Colby, Thomas

PY - 2002/9

Y1 - 2002/9

N2 - Objective: To present a case of pulmonary artery aneurysms (PAAs) in a child with Behcet's disease (BD). Nature of the study: Case report and review of the literature. Materials and methods: The patient had a complete autopsy, drug screen and serological testing. A medical history was obtained and the literature was reviewed. Results: A 10-year-old African-American boy had massive hemoptysis while at home and died shortly thereafter in the emergency department of a local hospital. He had had two other episodes of hemoptysis in the past 2 months. At autopsy, he had bilateral inflammatory aneurysms of the lower lobe branches of the pulmonary arteries. The left aneurysm had eroded into the adjacent bronchus and accounted for the fatal hemoptysis. The right ventricle had endocardial fibrosis. Systemic vasculitis was absent. The child did not have oral, genital, eye or skin lesions at autopsy, or by clinical history. Based on the autopsy findings, a diagnosis of BD was made. Conclusions: We present the very unusual case of a 10-year-old African-American boy who died from hemoptysis resulting from bilateral pulmonary aneurysms caused by BD.

AB - Objective: To present a case of pulmonary artery aneurysms (PAAs) in a child with Behcet's disease (BD). Nature of the study: Case report and review of the literature. Materials and methods: The patient had a complete autopsy, drug screen and serological testing. A medical history was obtained and the literature was reviewed. Results: A 10-year-old African-American boy had massive hemoptysis while at home and died shortly thereafter in the emergency department of a local hospital. He had had two other episodes of hemoptysis in the past 2 months. At autopsy, he had bilateral inflammatory aneurysms of the lower lobe branches of the pulmonary arteries. The left aneurysm had eroded into the adjacent bronchus and accounted for the fatal hemoptysis. The right ventricle had endocardial fibrosis. Systemic vasculitis was absent. The child did not have oral, genital, eye or skin lesions at autopsy, or by clinical history. Based on the autopsy findings, a diagnosis of BD was made. Conclusions: We present the very unusual case of a 10-year-old African-American boy who died from hemoptysis resulting from bilateral pulmonary aneurysms caused by BD.

KW - Behcet's disease

KW - Death-sudden

KW - Hughes-Stovin syndrome

KW - Pulmonary arteritis

KW - Pulmonary hemorrhage

UR - http://www.scopus.com/inward/record.url?scp=0036754203&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036754203&partnerID=8YFLogxK

U2 - 10.1016/S1054-8807(02)00117-5

DO - 10.1016/S1054-8807(02)00117-5

M3 - Article

C2 - 12361841

AN - SCOPUS:0036754203

VL - 11

SP - 296

EP - 299

JO - Cardiovascular Pathology

JF - Cardiovascular Pathology

SN - 1054-8807

IS - 5

ER -