Fatal diffuse invasive gastrointestinal candidiasis masking as ileus after bone marrow transplantation

John K. DiBaise, Eamonn M.M. Quigley

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

High-dose cytotoxic chemotherapy has increased the incidence of candidal infections that make neutropenic patients very sick and may kill them. We report fatal invasive candidiasis involving the entire alimentary tract after autologous bone marrow transplantation in a young woman with breast cancer. Illustrated are the significance of fungal infections in this patient population, the potential for Candida albicans to invade the entire gastrointestinal tract, and the potential role of endoscopy in the early diagnosis of these often catastrophic infections. We also suggest that diffuse, invasive candidiasis should be considered in the differential diagnosis of ileus in the immunocompromised patient.

Original languageEnglish (US)
Pages (from-to)165-168
Number of pages4
JournalJournal of clinical gastroenterology
Volume24
Issue number3
DOIs
StatePublished - Apr 1 1997

Keywords

  • Bone marrow transplantation
  • Candidiasis
  • Chemotherapy
  • Endoscopy
  • Ileus

ASJC Scopus subject areas

  • Gastroenterology

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