Fat-containing lesions of the liver

Radiologic-pathologic correlation

Srinivasa R. Prasad, Hanlin Wang, Humberto Rosas, Christine O. Menias, Vamsi R. Narra, William D. Middleton, Jay Heiken

Research output: Contribution to journalArticle

159 Citations (Scopus)

Abstract

Fat-containing tumors of the liver are a heterogeneous group of tumors with characteristic histologic features, variable biologic profiles, and variable imaging findings. Benign liver lesions that contain fat include focal or geographic fatty change (steatosis), pseudolesions due to post-operative packing material (omentum), adenoma, focal nodular hyperplasia, lipoma, angiomyolipoma, cystic teratoma, hepatic adrenal rest tumor, pseudolipoma of the Glisson capsule, and xanthomatous lesions in Langerhans cell histiocytosis. Malignant liver lesions that can contain fat include hepatocellular carcinoma, primary and metastatic liposarcoma, and hepatic metastases. Identification of fat within a liver lesion can be critical in characterization of the lesion. The imaging characteristics of a lesion coupled with the pattern of intratumoral fatty change are helpful in narrowing the differential diagnosis. Although the presence of fat can be demonstrated with computed tomography or ultrasound, magnetic resonance imaging is the most specific imaging technique for demonstration of both microscopic and macroscopic fat.

Original languageEnglish (US)
Pages (from-to)321-331
Number of pages11
JournalRadiographics
Volume25
Issue number2
DOIs
StatePublished - Jan 1 2005
Externally publishedYes

Fingerprint

Fats
Liver
Adrenal Rest Tumor
Focal Nodular Hyperplasia
Angiomyolipoma
Liposarcoma
Langerhans Cell Histiocytosis
Omentum
Lipoma
Teratoma
Adenoma
Capsules
Hepatocellular Carcinoma
Neoplasms
Differential Diagnosis
Tomography
Magnetic Resonance Imaging
Neoplasm Metastasis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Prasad, S. R., Wang, H., Rosas, H., Menias, C. O., Narra, V. R., Middleton, W. D., & Heiken, J. (2005). Fat-containing lesions of the liver: Radiologic-pathologic correlation. Radiographics, 25(2), 321-331. https://doi.org/10.1148/rg.252045083

Fat-containing lesions of the liver : Radiologic-pathologic correlation. / Prasad, Srinivasa R.; Wang, Hanlin; Rosas, Humberto; Menias, Christine O.; Narra, Vamsi R.; Middleton, William D.; Heiken, Jay.

In: Radiographics, Vol. 25, No. 2, 01.01.2005, p. 321-331.

Research output: Contribution to journalArticle

Prasad, SR, Wang, H, Rosas, H, Menias, CO, Narra, VR, Middleton, WD & Heiken, J 2005, 'Fat-containing lesions of the liver: Radiologic-pathologic correlation', Radiographics, vol. 25, no. 2, pp. 321-331. https://doi.org/10.1148/rg.252045083
Prasad SR, Wang H, Rosas H, Menias CO, Narra VR, Middleton WD et al. Fat-containing lesions of the liver: Radiologic-pathologic correlation. Radiographics. 2005 Jan 1;25(2):321-331. https://doi.org/10.1148/rg.252045083
Prasad, Srinivasa R. ; Wang, Hanlin ; Rosas, Humberto ; Menias, Christine O. ; Narra, Vamsi R. ; Middleton, William D. ; Heiken, Jay. / Fat-containing lesions of the liver : Radiologic-pathologic correlation. In: Radiographics. 2005 ; Vol. 25, No. 2. pp. 321-331.
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