Family histories of diabetes mellitus and breast cancer and incidence of postmenopausal breast cancer

Thomas A. Sellers, Kristin E. Anderson, Janet E Olson, Aaron R. Folsom

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

Diabetes-associated endocrine factors may influence the growth of some breast tumors. Therefore, one might expect an association of family history of diabetes mellitus with breast cancer incidence. We analyzed data from a cohort study of 41,837 women ages 55-69 years. During 10 years of follow-up, we identified 1,013 incident cases of breast cancer. There was no consistent association between family history of diabetes mellitus and family history of breast cancer, except among sisters. Women with a family history of diabetes had a higher prevalence of breast cancer risk factors, but family history of diabetes was not associated with risk of postmenopausal breast cancer, regardless of family history of breast cancer status.

Original languageEnglish (US)
Pages (from-to)102-105
Number of pages4
JournalEpidemiology
Volume9
Issue number1
StatePublished - Jan 1998
Externally publishedYes

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Keywords

  • Breast neoplasms
  • Cohort study
  • Diabetes mellitus
  • Family history
  • Obesity
  • Tumor receptor

ASJC Scopus subject areas

  • Epidemiology

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