Adrenoleukodystrophy (ALD) must be considered in the diagnosis of men with progressive nervous system disease. We found the biochemical defect characteristic of ALD in two brothers with spastic paraparesis of late adult onset. Family study then revealed other affected men and asymptomatic heterozygotes in a pattern that conformed to an X-linked pattern of inheritance.
|Original language||English (US)|
|Number of pages||3|
|State||Published - Aug 1985|
ASJC Scopus subject areas
- Clinical Neurology