Familial spastic paraparesis: An adrenoleukodystrophy phenotype?

Brian P. O’Neill, Jerry W. Swanson, Frank R. Brown, John W. Griffin, Hugo W. Moser

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

Adrenoleukodystrophy (ALD) must be considered in the diagnosis of men with progressive nervous system disease. We found the biochemical defect characteristic of ALD in two brothers with spastic paraparesis of late adult onset. Family study then revealed other affected men and asymptomatic heterozygotes in a pattern that conformed to an X-linked pattern of inheritance.

Original languageEnglish (US)
Pages (from-to)1233-1235
Number of pages3
JournalNeurology
Volume35
Issue number8
StatePublished - Aug 1985

ASJC Scopus subject areas

  • Clinical Neurology

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  • Cite this

    O’Neill, B. P., Swanson, J. W., Brown, F. R., Griffin, J. W., & Moser, H. W. (1985). Familial spastic paraparesis: An adrenoleukodystrophy phenotype? Neurology, 35(8), 1233-1235.