Familial hemiplegic migraine, neuropsychiatric symptoms, and erdheim-chester disease

David F. Black, Simon Kung, Christopher L. Sola, Michael J. Bostwick, Jerry W. Swanson

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

We report the occurrence of unilateral cerebral hemisphere edema with subsequent cortical laminar necrosis in the setting of familial hemiplegic migraine (FHM) and permanent neurologic sequelae after resolution of an attack in 1 patient. Contemporaneous with this severe attack of FHM, the patient was found to exhibit multiple systemic and neurological symptoms referable to Erdheim-Chester disease (a rare non-Langerhans cell histiocytosis) that was confirmed by bone biopsy. This case demonstrates the severity possible with a migrainous infarction associated with FHM. The co-occurrence of two such rare entities in 1 patient suggests a possible relationship.

Original languageEnglish (US)
Pages (from-to)911-915
Number of pages5
JournalHeadache
Volume44
Issue number9
DOIs
StatePublished - Oct 1 2004

Keywords

  • Erdheim-Chester Disease
  • Familial hemiplegic migraine
  • Migrainous infarction

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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