Familial dermatomyositis

Stephanie Plamondon, Peter B. Dent, Ann M. Reed

Research output: Contribution to journalArticle

16 Scopus citations


Susceptibility, response to therapy, prognosis, and natural history of connective tissue diseases are variably linked to histocompatibility antigens (HLA), although the precise role that such genes play is still not clear. In juvenile dermatomyositis (JDMS) there are few reports of both concordance and discordance in identical twins and occurrence in more than one family member. To further document the familial occurrence of JDMS, we describe 2 sisters, one with classical JDMS and the other with amyopathic dermatomyositis. The 2 patients were shown to share the HLA-DQA1*0501 allele, known to be associated with susceptibility to JDMS.

Original languageEnglish (US)
Pages (from-to)2691-2692
Number of pages2
JournalJournal of Rheumatology
Issue number12
StatePublished - Dec 17 1999


  • Amyopathic
  • Dermatomyositis
  • Familial
  • HLA
  • Juvenile dermatomyositis

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

Fingerprint Dive into the research topics of 'Familial dermatomyositis'. Together they form a unique fingerprint.

  • Cite this

    Plamondon, S., Dent, P. B., & Reed, A. M. (1999). Familial dermatomyositis. Journal of Rheumatology, 26(12), 2691-2692.