Failure of Signal-Averaged Electrocardiography With Use of Time-Domain Variables to Predict Inducible Ventricular Tachycardia in Patients With Conduction Defects

Steve R. Ommen, Stephen C. Hammill, Kent R. Bailey

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

To extend the application of signal-averaged electrocardiography (SAECG) to patients with ventricular conduction defects by analysis of electrocardiographic (ECG) time-domain variables. In 123 consecutive patients with a QRS duration of 118 ms or more on a resting ECG and without evidence of an accessory pathway, SAECG was done at the time of electrophysiologic (EP) study. For EP testing, up to three stimuli were delivered during two paced drives from two right ventricular sites. A “positive” EP result was defined as monomorphic ventricular tachycardia that lasted for more than 30 seconds or necessitated intervention. Data were obtained for four time-domain variables. All variables were analyzed for differences between patients with EP-positive and those with EP-negative results. Unfiltered QRS duration was the only time-domain ECG variable that was statistically different (P= 0.02) between patients with EP-positive and those with EP-negative results (141.3 and 147.8 ms, respectively); this difference persisted when patients with right bundle branch block were excluded from analysis. This finding is the opposite of previously reported observations. When only patients with ischemic heart disease were analyzed, no SAECG variables were significantly different between patients with inducible ventricular tachycardia and those without it. High-resolution ECG time-domain variables cannot be used to predict inducibility of ventricular tachycardia during EP testing in patients with conduction defects.

Original languageEnglish (US)
Pages (from-to)132-136
Number of pages5
JournalMayo Clinic proceedings
Volume70
Issue number2
DOIs
StatePublished - Jan 1 1995

Keywords

  • ECG
  • EP
  • RBBB
  • SAECG
  • electrocardiogram
  • electrophysiologic
  • right bundle branch block
  • signal-averaged electrocardiography

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Failure of Signal-Averaged Electrocardiography With Use of Time-Domain Variables to Predict Inducible Ventricular Tachycardia in Patients With Conduction Defects'. Together they form a unique fingerprint.

  • Cite this