Factor VIII-related antigen in Kaposi's sarcoma in young homosexual men

Thomas J Flotte, V. A. Hatcher, A. E. Friedman Kien

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Abstract

This study investigated the histogenesis of the Kaposi's sarcomas occurring in young homosexual men. Paraffin sections of seven tumors were stained for factor VIII-related antigen by the unlabeled peroxidase antiperoxidase method. Both the spindle cell component and the cells lining vascular channels contained factor VIII-related antigen, a marker for endothelial cells. Our study supports the hypothesis that both components of Kaposi's sarcoma are of endothelial cell origin.

Original languageEnglish (US)
Pages (from-to)180-182
Number of pages3
JournalArchives of Dermatology
Volume120
Issue number2
DOIs
StatePublished - 1984
Externally publishedYes

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ASJC Scopus subject areas

  • Dermatology

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