Factor VIII-related antigen in Kaposi's sarcoma in young homosexual men

Thomas J Flotte, V. A. Hatcher, A. E. Friedman Kien

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

This study investigated the histogenesis of the Kaposi's sarcomas occurring in young homosexual men. Paraffin sections of seven tumors were stained for factor VIII-related antigen by the unlabeled peroxidase antiperoxidase method. Both the spindle cell component and the cells lining vascular channels contained factor VIII-related antigen, a marker for endothelial cells. Our study supports the hypothesis that both components of Kaposi's sarcoma are of endothelial cell origin.

Original languageEnglish (US)
Pages (from-to)180-182
Number of pages3
JournalArchives of Dermatology
Volume120
Issue number2
DOIs
StatePublished - 1984
Externally publishedYes

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Kaposi's Sarcoma
von Willebrand Factor
Endothelial Cells
Cellular Structures
Paraffin
Peroxidase
Blood Vessels
Neoplasms
Sexual Minorities

ASJC Scopus subject areas

  • Dermatology

Cite this

Factor VIII-related antigen in Kaposi's sarcoma in young homosexual men. / Flotte, Thomas J; Hatcher, V. A.; Friedman Kien, A. E.

In: Archives of Dermatology, Vol. 120, No. 2, 1984, p. 180-182.

Research output: Contribution to journalArticle

Flotte, Thomas J ; Hatcher, V. A. ; Friedman Kien, A. E. / Factor VIII-related antigen in Kaposi's sarcoma in young homosexual men. In: Archives of Dermatology. 1984 ; Vol. 120, No. 2. pp. 180-182.
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