Faces of emotion in Parkinsons disease: Micro-expressivity and bradykinesia during voluntary facial expressions

Dawn Bowers, Kimberly Miller, Wendelyn Bosch, Didem Gokcay, Otto Pedraza, Utaka Springer, Michael Okun

Research output: Contribution to journalArticle

34 Scopus citations

Abstract

In humans, the neural circuitry underlying facial expressions differs, depending on whether facial expressions are spontaneously (i.e., limbic, subcortical) or voluntarily initiated (i.e., frontal cortex). Previous investigators have suggested that the "masked face" of Parkinson's disease involves spontaneous, but not intentional, facial expressions. In contrast, we hypothesized that intentional facial expressions may be slowed (bradykinetic) and involve less movement, in much the same way that other intentional movements are affected by Parkinson's disease. To test this hypothesis, we used sophisticated computer imaging techniques to quantify dynamic facial movement. Relative to controls, Parkinson patients had reduced facial movement (entropy) and were significantly slowed in reaching a peak expression (i.e., bradykinesia). These findings are consistent with the view that the basal ganglia play a role in affecting intentional facial movements. This possibly occurs because of diminished efficiency and/or activation of face representation areas in the frontal cortical regions (i.e., motor, premotor, and supplementary motor area) or because of movement-based suppression secondary to dopaminergic reduction in frontostriatal pathways. Taken together, the characterization of Parkinson's disease as a model system for the neuroanatomic dissociation between voluntary and spontaneous expressions may be unjustified.

Original languageEnglish (US)
Pages (from-to)765-773
Number of pages9
JournalJournal of the International Neuropsychological Society
Volume12
Issue number6
DOIs
StatePublished - Nov 2006

Keywords

  • Affect
  • Basal ganglia
  • Digitizing
  • Entropy
  • Movement
  • Spontaneous

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Psychology
  • Clinical Neurology
  • Psychiatry and Mental health

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