Eyelid Melanoma in the United States: A National Cancer Database Analysis

Jeremie D. Oliver, Daniel Boczar, Andrea Sisti, Maria T. Huayllani, David J. Restrepo, Aaron C. Spaulding, Emmanuel Gabriel, Sanjay Bagaria, Brian D. Rinker, Antonio J. Forte

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Abstract

BACKGROUND: Eyelid melanoma (EM) is a rare condition that accounts for <1% of all cutaneous melanomas. In this analysis, patients diagnosed with EM in the United States were compared to those with other melanomas in the head and neck. METHODS: The National Cancer Database was used to select patients with head and neck melanoma from 2004 to 2015. RESULTS: A total of 137,233 patients met the criteria of the study. Among them, 2694 were diagnosed with EM (2%) and 134,539 in other head and neck locations (98%). Regarding the patients with EM, the mean age was 68.56 years (standard deviation 14.04). A greater number of them were treated in Academic/Research Programs (53.6%), insured by Medicare (55.7%), tumor in situ (52.2%), stage 0 (49%), and without ulceration (75.9%). The mean time to treatment commencement was 18.96 days for EM compared to 14.4 days for other melanoma in the head and neck regions (P < 0.001). There was a greater proportion of EM in female patients (odds ratio [OR] 2.371 [2.191-2.566], P < 0.001), compared to male; age greater than 80 years (OR 1.622 [1.360-1.934], P < 0.001) compared to 0 to 49 years. Moreover, EM was an independent predictor for treatment in Academic/Research Programs (OR 1.258 [1.160-1.365], P < 0.001) and diagnosis at autopsy (OR 1.414 [1.083-1.847], P = 0.011) compared to other melanoma in the head and neck region. CONCLUSION: These novel findings have the potential to guide clinical decision making in head and neck melanoma management.

Original languageEnglish (US)
Pages (from-to)2412-2415
Number of pages4
JournalThe Journal of craniofacial surgery
Volume30
Issue number8
DOIs
StatePublished - Nov 1 2019

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ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology

Cite this

Oliver, J. D., Boczar, D., Sisti, A., Huayllani, M. T., Restrepo, D. J., Spaulding, A. C., Gabriel, E., Bagaria, S., Rinker, B. D., & Forte, A. J. (2019). Eyelid Melanoma in the United States: A National Cancer Database Analysis. The Journal of craniofacial surgery, 30(8), 2412-2415. https://doi.org/10.1097/SCS.0000000000005673