Abstract
The prognostic significance of extra-medullary chronic lymphocytic leukemia (EM-CLL) is unknown. We conducted a Medline database systematic search analyzing English language articles published between 1975 and 2012 identifying 192 cases. Patients with EM-CLL were more commonly treated than not (p<. .001). Skin and central nervous system (CNS) were the most commonly reported sites of organ involvement. Survival after diagnosis of EM-CLL appeared to depend on the site of EM involvement. Prospective evaluation and further studies of EM-CLL are warranted.
Original language | English (US) |
---|---|
Pages (from-to) | 299-303 |
Number of pages | 5 |
Journal | Leukemia Research |
Volume | 38 |
Issue number | 3 |
DOIs | |
State | Published - Mar 2014 |
Keywords
- CLL
- Chronic lymphocytic leukemia
- Extra-medullary
- Prognosis
ASJC Scopus subject areas
- Hematology
- Oncology
- Cancer Research