Extracellular RNAs: Development as biomarkers of human disease

Joseph F. Quinn; Tushar Patel; David Wong; Saumya Das; Jane E. Freedman; Louise C. Laurent; Bob S. Carter; Fred Hochberg; Kendall Van Keuren-Jensen; Matt Huentelman; Robert Spetzler; M. Yashar S. Kalani; Jorge Arango; P. David Adelson; Howard L. Weiner; Roopali Gandhi; Beatrice Goilav; Chaim Putterman; Julie A. Saugstad

doi:10.3402/jev.v4.27495

Extracellular RNAs: Development as biomarkers of human disease

Joseph F. Quinn, Tushar Patel, David Wong, Saumya Das, Jane E. Freedman, Louise C. Laurent, Bob S. Carter, Fred Hochberg, Kendall Van Keuren-Jensen, Matt Huentelman, Robert Spetzler, M. Yashar S. Kalani, Jorge Arango, P. David Adelson, Howard L. Weiner, Roopali Gandhi, Beatrice Goilav, Chaim Putterman, Julie A. Saugstad

Gastroenterology and Hepatology

Research output: Contribution to journal › Article › peer-review

43 Scopus citations

Abstract

Ten ongoing studies designed to test the possibility that extracellular RNAs may serve as biomarkers in human disease are described. These studies, funded by the NIH Common Fund Extracellular RNA Communication Program, examine diverse extracellular body fluids, including plasma, serum, urine and cerebrospinal fluid. The disorders studied include hepatic and gastric cancer, cardiovascular disease, chronic kidney disease, neurodegenerative disease, brain tumours, intracranial haemorrhage,multiple sclerosis and placental disorders. Progress to date and the plans for future studies are outlined.

Original language	English (US)
Article number	27495
Journal	Journal of Extracellular Vesicles
Volume	4
Issue number	1
DOIs	https://doi.org/10.3402/jev.v4.27495
State	Published - 2015

Keywords

Biomarkers
ERCC
ExRNA
Extracellular RNA

ASJC Scopus subject areas

Histology
Cell Biology

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Quinn, J. F., Patel, T., Wong, D., Das, S., Freedman, J. E., Laurent, L. C., Carter, B. S., Hochberg, F., Van Keuren-Jensen, K., Huentelman, M., Spetzler, R., Kalani, M. Y. S., Arango, J., Adelson, P. D., Weiner, H. L., Gandhi, R., Goilav, B., Putterman, C., & Saugstad, J. A. (2015). Extracellular RNAs: Development as biomarkers of human disease. Journal of Extracellular Vesicles, 4(1), Article 27495. https://doi.org/10.3402/jev.v4.27495

Quinn, JF, Patel, T, Wong, D, Das, S, Freedman, JE, Laurent, LC, Carter, BS, Hochberg, F, Van Keuren-Jensen, K, Huentelman, M, Spetzler, R, Kalani, MYS, Arango, J, Adelson, PD, Weiner, HL, Gandhi, R, Goilav, B, Putterman, C & Saugstad, JA 2015, 'Extracellular RNAs: Development as biomarkers of human disease', Journal of Extracellular Vesicles, vol. 4, no. 1, 27495. https://doi.org/10.3402/jev.v4.27495

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AU - Laurent, Louise C.

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AU - Van Keuren-Jensen, Kendall

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Extracellular RNAs: Development as biomarkers of human disease

Abstract

Keywords

ASJC Scopus subject areas

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