Extensive metabolic and neuropsychological abnormalities associated with discrete infarction of the genu of the internal capsule

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36 Scopus citations

Abstract

Objective - The clinical presentation of capsular genu infarct varies. Prominent faciolingual weakness and subcortical dementia are the rule, but symptoms depend on the precise location and extension of the lesion beyond the genu. The aim was to characterise the radiographic, electroencephalographic, and neuropsychometric abnormalities in a woman who had a history of recurrent transient memory loss. Method - Case report. Results - Magnetic resonance imaging showed an infarct in the genu of the left internal capsule. Positron emission tomography scan demonstrated decreased metabolic activity in the ipsilateral temporal, occipitotemporal, and contralateral cerebellar hemispheres. Electroencephalography showed intermittent rhythmic delta activity in the left frontotemporal region, and findings on neuropsychometric evaluation were consistent with cognitive impairment. Follow up evaluation 7 months after the stroke showed improvement in some areas of the cognitive domain, but residual neuropsychometric and neurophysiological abnormalities persisted. Conclusion - This case illustrates that cerebral and cerebellar diaschisis may contribute to the symptomatic presentation and recovery from capsular genu infarct, although its precise role remains elusive.

Original languageEnglish (US)
Pages (from-to)658-662
Number of pages5
JournalJournal of Neurology Neurosurgery and Psychiatry
Volume71
Issue number5
DOIs
StatePublished - Nov 2001

Keywords

  • Amnestic syndrome
  • Capsular genu infarct
  • Diaschisis

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology
  • Psychiatry and Mental health

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