Expression of H-2.7(G) antigen on H-2(k) erythrocytes after in vivo activation of C4

S. Yokota, J. Gorski, C. David

Research output: Contribution to journalArticle

Abstract

Erythrocyte antigen H-2.7(G) is a determinant on the C4d fragment of the fourth component of complement and maps to the S region of the mouse MHC. The C4-deficient S(k)-strains are genotypically H-2.7+ but lack the determinant on erythrocyte. In vivo injection of aggregated human γ-globulin into S(k)-strains activates the classical complement pathway and thereby results in transfer of the H-2.7 antigen onto erythrocytes. The highest hemagglutination titer was obtained when the mice were bled to 5 to 10 hr after injection of 200 μg of AHGG.

Original languageEnglish (US)
Pages (from-to)450-451
Number of pages2
JournalTransplantation
Volume32
Issue number5
StatePublished - 1981

Fingerprint

H-2 Antigens
Erythrocytes
Classical Complement Pathway
Injections
Globulins
Hemagglutination
H antigen

ASJC Scopus subject areas

  • Immunology
  • Transplantation

Cite this

Expression of H-2.7(G) antigen on H-2(k) erythrocytes after in vivo activation of C4. / Yokota, S.; Gorski, J.; David, C.

In: Transplantation, Vol. 32, No. 5, 1981, p. 450-451.

Research output: Contribution to journalArticle

Yokota, S, Gorski, J & David, C 1981, 'Expression of H-2.7(G) antigen on H-2(k) erythrocytes after in vivo activation of C4', Transplantation, vol. 32, no. 5, pp. 450-451.
Yokota, S. ; Gorski, J. ; David, C. / Expression of H-2.7(G) antigen on H-2(k) erythrocytes after in vivo activation of C4. In: Transplantation. 1981 ; Vol. 32, No. 5. pp. 450-451.
@article{fd10c6277f244746b3589d3bd2c7363b,
title = "Expression of H-2.7(G) antigen on H-2(k) erythrocytes after in vivo activation of C4",
abstract = "Erythrocyte antigen H-2.7(G) is a determinant on the C4d fragment of the fourth component of complement and maps to the S region of the mouse MHC. The C4-deficient S(k)-strains are genotypically H-2.7+ but lack the determinant on erythrocyte. In vivo injection of aggregated human γ-globulin into S(k)-strains activates the classical complement pathway and thereby results in transfer of the H-2.7 antigen onto erythrocytes. The highest hemagglutination titer was obtained when the mice were bled to 5 to 10 hr after injection of 200 μg of AHGG.",
author = "S. Yokota and J. Gorski and C. David",
year = "1981",
language = "English (US)",
volume = "32",
pages = "450--451",
journal = "Transplantation",
issn = "0041-1337",
publisher = "Lippincott Williams and Wilkins",
number = "5",

}

TY - JOUR

T1 - Expression of H-2.7(G) antigen on H-2(k) erythrocytes after in vivo activation of C4

AU - Yokota, S.

AU - Gorski, J.

AU - David, C.

PY - 1981

Y1 - 1981

N2 - Erythrocyte antigen H-2.7(G) is a determinant on the C4d fragment of the fourth component of complement and maps to the S region of the mouse MHC. The C4-deficient S(k)-strains are genotypically H-2.7+ but lack the determinant on erythrocyte. In vivo injection of aggregated human γ-globulin into S(k)-strains activates the classical complement pathway and thereby results in transfer of the H-2.7 antigen onto erythrocytes. The highest hemagglutination titer was obtained when the mice were bled to 5 to 10 hr after injection of 200 μg of AHGG.

AB - Erythrocyte antigen H-2.7(G) is a determinant on the C4d fragment of the fourth component of complement and maps to the S region of the mouse MHC. The C4-deficient S(k)-strains are genotypically H-2.7+ but lack the determinant on erythrocyte. In vivo injection of aggregated human γ-globulin into S(k)-strains activates the classical complement pathway and thereby results in transfer of the H-2.7 antigen onto erythrocytes. The highest hemagglutination titer was obtained when the mice were bled to 5 to 10 hr after injection of 200 μg of AHGG.

UR - http://www.scopus.com/inward/record.url?scp=0019787777&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019787777&partnerID=8YFLogxK

M3 - Article

C2 - 6173940

AN - SCOPUS:0019787777

VL - 32

SP - 450

EP - 451

JO - Transplantation

JF - Transplantation

SN - 0041-1337

IS - 5

ER -