Abstract
Amyloid precursor protein (APP) is evolutionary conserved protein expressed in endothelial cells of cerebral and peripheral arteries. In this review, we discuss mechanisms responsible for expression and proteolytic cleavage of APP in endothelial cells. We focus on physiological and pathological implications of APP expression in vascular endothelium.
Original language | English (US) |
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Pages (from-to) | 20-32 |
Number of pages | 13 |
Journal | Physiology |
Volume | 32 |
Issue number | 1 |
DOIs | |
State | Published - Jan 2017 |
ASJC Scopus subject areas
- Physiology