Exploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies: A convening of the Alzheimer's Association & Alzheimer's Drug Discovery Foundation

Heather M. Snyder, Tim Ahles, Stuart Calderwood, Maria C. Carrillo, Honglei Chen, Chung Chou H Chang, Suzanne Craft, Philip De Jager, Jane A. Driver, Howard Fillit, David S Knopman, Michael Lotze, Mary C. Tierney, Suzana Petanceska, Andrew Saykin, Sudha Seshadri, Diana Shineman, Mary Ganguli

Research output: Contribution to journalReview article

12 Citations (Scopus)

Abstract

Recent population studies suggest an intriguing inverse relationship between several types of cancer and neurodegenerative diseases, including Alzheimer's disease. Understanding the intersection of the underlying biology for these two distinct families of diseases with one another may offer novel approaches to identify new therapeutic approaches and possible opportunities to repurpose existing drug candidates. The Alzheimer's Association and the Alzheimer's Drug Discovery Foundation convened a one-day workshop to delve into this discussion. Workshop participants outlined research focus areas, potential collaborations, and partnerships for future action.

Original languageEnglish (US)
Pages (from-to)267-273
Number of pages7
JournalAlzheimer's and Dementia
Volume13
Issue number3
DOIs
StatePublished - Mar 1 2017

Fingerprint

Drug Discovery
Dementia
Alzheimer Disease
Drug Repositioning
Education
Neurodegenerative Diseases
Neoplasms
Therapeutics
Research
Population
Nexus

Keywords

  • Alzheimer's disease
  • Biological mechanisms
  • Cancer
  • Epidemiology
  • Genetics
  • Oncology
  • Repurpose therapy

ASJC Scopus subject areas

  • Epidemiology
  • Health Policy
  • Developmental Neuroscience
  • Geriatrics and Gerontology
  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Psychiatry and Mental health

Cite this

Exploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies : A convening of the Alzheimer's Association & Alzheimer's Drug Discovery Foundation. / Snyder, Heather M.; Ahles, Tim; Calderwood, Stuart; Carrillo, Maria C.; Chen, Honglei; Chang, Chung Chou H; Craft, Suzanne; De Jager, Philip; Driver, Jane A.; Fillit, Howard; Knopman, David S; Lotze, Michael; Tierney, Mary C.; Petanceska, Suzana; Saykin, Andrew; Seshadri, Sudha; Shineman, Diana; Ganguli, Mary.

In: Alzheimer's and Dementia, Vol. 13, No. 3, 01.03.2017, p. 267-273.

Research output: Contribution to journalReview article

Snyder, HM, Ahles, T, Calderwood, S, Carrillo, MC, Chen, H, Chang, CCH, Craft, S, De Jager, P, Driver, JA, Fillit, H, Knopman, DS, Lotze, M, Tierney, MC, Petanceska, S, Saykin, A, Seshadri, S, Shineman, D & Ganguli, M 2017, 'Exploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies: A convening of the Alzheimer's Association & Alzheimer's Drug Discovery Foundation', Alzheimer's and Dementia, vol. 13, no. 3, pp. 267-273. https://doi.org/10.1016/j.jalz.2016.11.002
Snyder, Heather M. ; Ahles, Tim ; Calderwood, Stuart ; Carrillo, Maria C. ; Chen, Honglei ; Chang, Chung Chou H ; Craft, Suzanne ; De Jager, Philip ; Driver, Jane A. ; Fillit, Howard ; Knopman, David S ; Lotze, Michael ; Tierney, Mary C. ; Petanceska, Suzana ; Saykin, Andrew ; Seshadri, Sudha ; Shineman, Diana ; Ganguli, Mary. / Exploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies : A convening of the Alzheimer's Association & Alzheimer's Drug Discovery Foundation. In: Alzheimer's and Dementia. 2017 ; Vol. 13, No. 3. pp. 267-273.
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