Abstract
At a symposium convened on March 8, 2007 by the Institute on Aging at the University of Pennsylvania, researchers from the University's Schools of Medicine and Veterinary Medicine explored the convergence of aging research emerging from the two schools. Studies in human patients, animal models, and companion animals have revealed different but complementary aspects of the aging process, ranging from fundamental biologic aspects of aging to the treatment of age-related diseases, both experimentally and in clinical practice. Participants concluded that neither animal nor human research alone will provide answers to most questions about the aging process. Instead, an optimal translational research model supports a bidirectional flow of information from animal models to clinical research.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1-5 |
| Number of pages | 5 |
| Journal | Alzheimer's and Dementia |
| Volume | 4 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 2008 |
| Externally published | Yes |
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Keywords
- Aging related diseases
- Model systems for aging research
- Normal aging
- Organ specific mechanisms of aging in humans and animals
ASJC Scopus subject areas
- Epidemiology
- Health Policy
- Developmental Neuroscience
- Clinical Neurology
- Geriatrics and Gerontology
- Cellular and Molecular Neuroscience
- Psychiatry and Mental health
Cite this
Exploring human/animal intersections : Converging lines of evidence in comparative models of aging. / Trojanowski, John Q.; Hendricks, Joan C.; Jedrziewski, Kathryn; Johnson, F. Brad; Michel, Kathryn E.; Hess, Rebecka S.; Cancro, Michael P.; Sleeper, Meg M.; Pignolo, Robert; Teff, Karen L.; Aguirre, Gustavo D.; Lee, Virginia M.Y.; Lawler, Dennis F.; Pack, Allan I.; Davies, Peter F.
In: Alzheimer's and Dementia, Vol. 4, No. 1, 01.01.2008, p. 1-5.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Exploring human/animal intersections
T2 - Converging lines of evidence in comparative models of aging
AU - Trojanowski, John Q.
AU - Hendricks, Joan C.
AU - Jedrziewski, Kathryn
AU - Johnson, F. Brad
AU - Michel, Kathryn E.
AU - Hess, Rebecka S.
AU - Cancro, Michael P.
AU - Sleeper, Meg M.
AU - Pignolo, Robert
AU - Teff, Karen L.
AU - Aguirre, Gustavo D.
AU - Lee, Virginia M.Y.
AU - Lawler, Dennis F.
AU - Pack, Allan I.
AU - Davies, Peter F.
PY - 2008/1/1
Y1 - 2008/1/1
N2 - At a symposium convened on March 8, 2007 by the Institute on Aging at the University of Pennsylvania, researchers from the University's Schools of Medicine and Veterinary Medicine explored the convergence of aging research emerging from the two schools. Studies in human patients, animal models, and companion animals have revealed different but complementary aspects of the aging process, ranging from fundamental biologic aspects of aging to the treatment of age-related diseases, both experimentally and in clinical practice. Participants concluded that neither animal nor human research alone will provide answers to most questions about the aging process. Instead, an optimal translational research model supports a bidirectional flow of information from animal models to clinical research.
AB - At a symposium convened on March 8, 2007 by the Institute on Aging at the University of Pennsylvania, researchers from the University's Schools of Medicine and Veterinary Medicine explored the convergence of aging research emerging from the two schools. Studies in human patients, animal models, and companion animals have revealed different but complementary aspects of the aging process, ranging from fundamental biologic aspects of aging to the treatment of age-related diseases, both experimentally and in clinical practice. Participants concluded that neither animal nor human research alone will provide answers to most questions about the aging process. Instead, an optimal translational research model supports a bidirectional flow of information from animal models to clinical research.
KW - Aging related diseases
KW - Model systems for aging research
KW - Normal aging
KW - Organ specific mechanisms of aging in humans and animals
UR - http://www.scopus.com/inward/record.url?scp=38049007391&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=38049007391&partnerID=8YFLogxK
U2 - 10.1016/j.jalz.2007.09.007
DO - 10.1016/j.jalz.2007.09.007
M3 - Article
C2 - 18631944
AN - SCOPUS:38049007391
VL - 4
SP - 1
EP - 5
JO - Alzheimer's and Dementia
JF - Alzheimer's and Dementia
SN - 1552-5260
IS - 1
ER -