Exploring human/animal intersections: Converging lines of evidence in comparative models of aging

John Q. Trojanowski; Joan C. Hendricks; Kathryn Jedrziewski; F. Brad Johnson; Kathryn E. Michel; Rebecka S. Hess; Michael P. Cancro; Meg M. Sleeper; Robert Pignolo; Karen L. Teff; Gustavo D. Aguirre; Virginia M.Y. Lee; Dennis F. Lawler; Allan I. Pack; Peter F. Davies

doi:10.1016/j.jalz.2007.09.007

Exploring human/animal intersections: Converging lines of evidence in comparative models of aging

John Q. Trojanowski, Joan C. Hendricks, Kathryn Jedrziewski, F. Brad Johnson, Kathryn E. Michel, Rebecka S. Hess, Michael P. Cancro, Meg M. Sleeper, Robert Pignolo, Karen L. Teff, Gustavo D. Aguirre, Virginia M.Y. Lee, Dennis F. Lawler, Allan I. Pack, Peter F. Davies

Hospital Internal Medicine

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

At a symposium convened on March 8, 2007 by the Institute on Aging at the University of Pennsylvania, researchers from the University's Schools of Medicine and Veterinary Medicine explored the convergence of aging research emerging from the two schools. Studies in human patients, animal models, and companion animals have revealed different but complementary aspects of the aging process, ranging from fundamental biologic aspects of aging to the treatment of age-related diseases, both experimentally and in clinical practice. Participants concluded that neither animal nor human research alone will provide answers to most questions about the aging process. Instead, an optimal translational research model supports a bidirectional flow of information from animal models to clinical research.

Original language	English (US)
Pages (from-to)	1-5
Number of pages	5
Journal	Alzheimer's and Dementia
Volume	4
Issue number	1
DOIs	https://doi.org/10.1016/j.jalz.2007.09.007
State	Published - Jan 2008

Keywords

Aging related diseases
Model systems for aging research
Normal aging
Organ specific mechanisms of aging in humans and animals

ASJC Scopus subject areas

Epidemiology
Health Policy
Developmental Neuroscience
Clinical Neurology
Geriatrics and Gerontology
Psychiatry and Mental health
Cellular and Molecular Neuroscience

Access to Document

10.1016/j.jalz.2007.09.007

Cite this

Trojanowski, J. Q., Hendricks, J. C., Jedrziewski, K., Johnson, F. B., Michel, K. E., Hess, R. S., Cancro, M. P., Sleeper, M. M., Pignolo, R., Teff, K. L., Aguirre, G. D., Lee, V. M. Y., Lawler, D. F., Pack, A. I., & Davies, P. F. (2008). Exploring human/animal intersections: Converging lines of evidence in comparative models of aging. Alzheimer's and Dementia, 4(1), 1-5. https://doi.org/10.1016/j.jalz.2007.09.007

Trojanowski, JQ, Hendricks, JC, Jedrziewski, K, Johnson, FB, Michel, KE, Hess, RS, Cancro, MP, Sleeper, MM, Pignolo, R, Teff, KL, Aguirre, GD, Lee, VMY, Lawler, DF, Pack, AI & Davies, PF 2008, 'Exploring human/animal intersections: Converging lines of evidence in comparative models of aging', Alzheimer's and Dementia, vol. 4, no. 1, pp. 1-5. https://doi.org/10.1016/j.jalz.2007.09.007

@article{f7bfd20be00d472e9fc715577662b447,

title = "Exploring human/animal intersections: Converging lines of evidence in comparative models of aging",

abstract = "At a symposium convened on March 8, 2007 by the Institute on Aging at the University of Pennsylvania, researchers from the University's Schools of Medicine and Veterinary Medicine explored the convergence of aging research emerging from the two schools. Studies in human patients, animal models, and companion animals have revealed different but complementary aspects of the aging process, ranging from fundamental biologic aspects of aging to the treatment of age-related diseases, both experimentally and in clinical practice. Participants concluded that neither animal nor human research alone will provide answers to most questions about the aging process. Instead, an optimal translational research model supports a bidirectional flow of information from animal models to clinical research.",

keywords = "Aging related diseases, Model systems for aging research, Normal aging, Organ specific mechanisms of aging in humans and animals",

author = "Trojanowski, {John Q.} and Hendricks, {Joan C.} and Kathryn Jedrziewski and Johnson, {F. Brad} and Michel, {Kathryn E.} and Hess, {Rebecka S.} and Cancro, {Michael P.} and Sleeper, {Meg M.} and Robert Pignolo and Teff, {Karen L.} and Aguirre, {Gustavo D.} and Lee, {Virginia M.Y.} and Lawler, {Dennis F.} and Pack, {Allan I.} and Davies, {Peter F.}",

year = "2008",

month = jan,

doi = "10.1016/j.jalz.2007.09.007",

language = "English (US)",

volume = "4",

pages = "1--5",

journal = "Alzheimer's and Dementia",

issn = "1552-5260",

publisher = "Elsevier Inc.",

number = "1",

}

TY - JOUR

T1 - Exploring human/animal intersections

T2 - Converging lines of evidence in comparative models of aging

AU - Trojanowski, John Q.

AU - Hendricks, Joan C.

AU - Jedrziewski, Kathryn

AU - Johnson, F. Brad

AU - Michel, Kathryn E.

AU - Hess, Rebecka S.

AU - Cancro, Michael P.

AU - Sleeper, Meg M.

AU - Pignolo, Robert

AU - Teff, Karen L.

AU - Aguirre, Gustavo D.

AU - Lee, Virginia M.Y.

AU - Lawler, Dennis F.

AU - Pack, Allan I.

AU - Davies, Peter F.

PY - 2008/1

Y1 - 2008/1

N2 - At a symposium convened on March 8, 2007 by the Institute on Aging at the University of Pennsylvania, researchers from the University's Schools of Medicine and Veterinary Medicine explored the convergence of aging research emerging from the two schools. Studies in human patients, animal models, and companion animals have revealed different but complementary aspects of the aging process, ranging from fundamental biologic aspects of aging to the treatment of age-related diseases, both experimentally and in clinical practice. Participants concluded that neither animal nor human research alone will provide answers to most questions about the aging process. Instead, an optimal translational research model supports a bidirectional flow of information from animal models to clinical research.

AB - At a symposium convened on March 8, 2007 by the Institute on Aging at the University of Pennsylvania, researchers from the University's Schools of Medicine and Veterinary Medicine explored the convergence of aging research emerging from the two schools. Studies in human patients, animal models, and companion animals have revealed different but complementary aspects of the aging process, ranging from fundamental biologic aspects of aging to the treatment of age-related diseases, both experimentally and in clinical practice. Participants concluded that neither animal nor human research alone will provide answers to most questions about the aging process. Instead, an optimal translational research model supports a bidirectional flow of information from animal models to clinical research.

KW - Aging related diseases

KW - Model systems for aging research

KW - Normal aging

KW - Organ specific mechanisms of aging in humans and animals

UR - http://www.scopus.com/inward/record.url?scp=38049007391&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=38049007391&partnerID=8YFLogxK

U2 - 10.1016/j.jalz.2007.09.007

DO - 10.1016/j.jalz.2007.09.007

M3 - Article

C2 - 18631944

AN - SCOPUS:38049007391

VL - 4

SP - 1

EP - 5

JO - Alzheimer's and Dementia

JF - Alzheimer's and Dementia

SN - 1552-5260

IS - 1

ER -

Exploring human/animal intersections: Converging lines of evidence in comparative models of aging

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this