TY - JOUR
T1 - Expert consensus for multi-modality imaging evaluation of cardiovascular complications of radiotherapy in adults
T2 - a report from the European Association of Cardiovascular Imaging and the American Society of Echocardiography.
AU - Lancellotti, Patrizio
AU - Nkomo, Vuyisile T.
AU - Badano, Luigi P.
AU - Bergler-Klein, Jutta
AU - Bogaert, Jan
AU - Davin, Laurent
AU - Cosyns, Bernard
AU - Coucke, Philippe
AU - Dulgheru, Raluca
AU - Edvardsen, Thor
AU - Gaemperli, Oliver
AU - Galderisi, Maurizio
AU - Griffin, Brian
AU - Heidenreich, Paul A.
AU - Nieman, Koen
AU - Plana, Juan C.
AU - Port, Steven C.
AU - Scherrer-Crosbie, Marielle
AU - Schwartz, Ronald G.
AU - Sebag, Igal A.
AU - Voigt, Jens Uwe
AU - Wann, Samuel
AU - Yang, Phillip C.
AU - American Society of Nuclear Cardiology, Society of Nuclear Cardiology
AU - Society for Cardiovascular Magnetic Resonance, for Cardiovascular Magnetic Resonance
AU - Society of Cardiovascular Computed Tomography, of Cardiovascular Computed Tomography
N1 - Funding Information:
Funding: No financial assistance was received to support this study.
PY - 2013/8
Y1 - 2013/8
N2 - Cardiac toxicity is one of the most concerning side effects of anti-cancer therapy. The gain in life expectancy obtained with anti-cancer therapy can be compromised by increased morbidity and mortality associated with its cardiac complications. While radiosensitivity of the heart was initially recognized only in the early 1970s, the heart is regarded in the current era as one of the most critical dose-limiting organs in radiotherapy. Several clinical studies have identified adverse clinical consequences of radiation-induced heart disease (RIHD) on the outcome of long-term cancer survivors. A comprehensive review of potential cardiac complications related to radiotherapy is warranted. An evidence-based review of several imaging approaches used to detect, evaluate, and monitor RIHD is discussed. Recommendations for the early identification and monitoring of cardiovascular complications of radiotherapy by cardiac imaging are also proposed.
AB - Cardiac toxicity is one of the most concerning side effects of anti-cancer therapy. The gain in life expectancy obtained with anti-cancer therapy can be compromised by increased morbidity and mortality associated with its cardiac complications. While radiosensitivity of the heart was initially recognized only in the early 1970s, the heart is regarded in the current era as one of the most critical dose-limiting organs in radiotherapy. Several clinical studies have identified adverse clinical consequences of radiation-induced heart disease (RIHD) on the outcome of long-term cancer survivors. A comprehensive review of potential cardiac complications related to radiotherapy is warranted. An evidence-based review of several imaging approaches used to detect, evaluate, and monitor RIHD is discussed. Recommendations for the early identification and monitoring of cardiovascular complications of radiotherapy by cardiac imaging are also proposed.
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U2 - 10.1093/ehjci/jet123
DO - 10.1093/ehjci/jet123
M3 - Article
C2 - 23847385
AN - SCOPUS:84886241887
SN - 2047-2404
VL - 14
SP - 721
EP - 740
JO - European Heart Journal Cardiovascular Imaging
JF - European Heart Journal Cardiovascular Imaging
IS - 8
ER -