Experimental carpal reverse-flow pedicle vascularized bone grafts. Part II: Bone blood flow measurement by radioactive-labeled microspheres in a canine model

Yuan Kun Tu, Allen T. Bishop, Teiji Kato, Mary L. Adams, Michael B. Wood

Research output: Contribution to journalArticle

38 Scopus citations

Abstract

Reverse-flow pedicle vascularized bone grafts (VBGs) from the radius, commonly used for carpal nonunion and avascular necrosis, provide superior clinical results. In this experimental study bone blood flow in canine distal radius VBGs was measured to determine the status of the bone circulation immediately after elevation (group 1) and 2 weeks later (group 2). Immediate VBG flow (group 1) was substantial, but significantly less than the contralateral undisturbed distal radius (8.42 mL/min/100 g and 16.53 mL/min/100 g, respectively). At 2 weeks after surgery (group 2) VBG flow was compared with nonvascularized control grafts. Vascularized bone graft flow was significantly higher than group 1 (mean, 33.72 mL/min/100 g). Minimal flow was seen in the conventional graft control (0.62 mL/min/100 g). This study demonstrates that reverse-flow pedicle radius VBG maintain enhanced bone circulation long-term. Given the similarity of human and canine distal radius vascular anatomy, these data support the clinical use of reverse-flow VBG for carpal pathology. Copyright (C) 2000 by the American Society for Surgery of the Hand.

Original languageEnglish (US)
Pages (from-to)46-54
Number of pages9
JournalJournal of Hand Surgery
Volume25
Issue number1
DOIs
StatePublished - Jan 2000

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

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