Expansile crosslinked polymersomes for pH sensitive delivery of doxorubicin

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

We report a new crosslinked polymersome with pH-responsive swelling properties through acidic hydrolysis of hydrophobic contents from the amphiphilic polymer chains. Its unique stability under physiological conditions and large swelling capability under low pH conditions give this polymersome promising potential for anticancer drug delivery.

Original languageEnglish (US)
Pages (from-to)245-249
Number of pages5
JournalBiomaterials Science
Volume4
Issue number2
DOIs
StatePublished - Feb 1 2016

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Doxorubicin
Swelling
Drug delivery
Hydrolysis
Polymers

ASJC Scopus subject areas

  • Materials Science(all)
  • Biomedical Engineering

Cite this

Expansile crosslinked polymersomes for pH sensitive delivery of doxorubicin. / Liu, Xifeng; Yaszemski, Michael J; Lu, Lichun.

In: Biomaterials Science, Vol. 4, No. 2, 01.02.2016, p. 245-249.

Research output: Contribution to journalArticle

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