Expanded traditional melanoma FISH testing versus CAP-QPCR to identify high-risk melanocytic lesions. / Sominidi-Damodaran, Sindhuja; Guo, Ruifeng; Meves, Alexander; Bridges, Alina G.In: International journal of dermatology, Vol. 56, No. 9, 09.2017, p. e182-e184.
Research output: Contribution to journal › Letter › peer-review
TY - JOUR
T1 - Expanded traditional melanoma FISH testing versus CAP-QPCR to identify high-risk melanocytic lesions
AU - Sominidi-Damodaran, Sindhuja
AU - Guo, Ruifeng
AU - Meves, Alexander
AU - Bridges, Alina G.
N1 - Funding Information: Borderline melanocytic tumors (BMT) are a heterogeneous group of lesions that can be diagnostically challenging. Although histopathology remains the gold standard for diagnosing melanocytic tumors and is sufficient for the vast majority of melanocytic lesions, adjuvant tools are sometimes useful for making a definitive diagnosis. One such tool for diagnosing BMT is fluorescent in-situ hybridization (FISH). In addition, cell adhesion phenotyping by quantitative PCR (CAP-QPCR) can identify high-risk melanocytic tumors at risk of regional metastasis. Here, our aim was to compare FISH and CAP-QPCR for their ability to identify high-risk BMT at diagnosis. This study was approved by the Institutional Review Board of Mayo Clinic. Funding Information: Conflicts of Interest Disclosure: None declared. Funding Source: This study was supported by the Mayo Clinic, Department of Dermatology, the Center for Clinical and Translational Science grant UL1TR000135 (AM), and generous gifts from Lucille and Smith Gibson, the Mendelin family, and Arnold and Kit Palmer. AM is the recipient of a Gerstner Family Foundation Career Development Award.
PY - 2017/9
Y1 - 2017/9
UR - http://www.scopus.com/inward/record.url?scp=85017137388&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85017137388&partnerID=8YFLogxK
U2 - 10.1111/ijd.13596
DO - 10.1111/ijd.13596
M3 - Letter
C2 - 28317107
AN - SCOPUS:85017137388
VL - 56
SP - e182-e184
JO - International Journal of Dermatology
JF - International Journal of Dermatology
SN - 0011-9059
IS - 9