Exercise training produces changes in free and conjugated catecholamines

Brent A Bauer, P. J. Rogers, T. D. Miller, A. A. Bove, G. M. Tyce

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

In dogs the concentrations of conjugated dopamine in plasma have previously been shown to increase after exercise training. This study was done to determine whether conjugated norepinephrine and epinephrine also increase. Fifteen dogs were randomly divided into training (N = 8) or sedentary (N = 7) groups. All dogs were exercised acutely for 5 min at 4 mpm with a 12% grade, following a 3-min warm-up, before and after either a 12-wk training or a 12-wk sedentary period. Free and conjugated catecholamines were determined in blood drawn at rest and during acute exercise using high-performance liquid chromatography (HPLC) with electrochemical detection. Before training, free norepinephrine, epinephrine, dopamine, and conjugated norephinephrine increased in plasma during acute exercise. Following the 12-wk training period, there were significant increases in free and conjugated dopamine and in conjugated norepinephrine in plasma taken at rest. There were no such increases in resting catecholamines after 12-wk sedentary period. After either training or sedentary periods, dogs responded to acute exercise with an increase in free norpinephrine and a decrease in conjugated norepinephrine. Thus, after training both conjugated norepinephrine and dopamine, but not conjugated epinephrine, increased in plasma. The data suggest that sulfation of catecholamines increases as a result of exercise training.

Original languageEnglish (US)
Pages (from-to)558-562
Number of pages5
JournalMedicine and Science in Sports and Exercise
Volume21
Issue number5
StatePublished - 1989

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Catecholamines
Norepinephrine
Exercise
Dopamine
Dogs
Epinephrine
High Pressure Liquid Chromatography

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Public Health, Environmental and Occupational Health
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Bauer, B. A., Rogers, P. J., Miller, T. D., Bove, A. A., & Tyce, G. M. (1989). Exercise training produces changes in free and conjugated catecholamines. Medicine and Science in Sports and Exercise, 21(5), 558-562.

Exercise training produces changes in free and conjugated catecholamines. / Bauer, Brent A; Rogers, P. J.; Miller, T. D.; Bove, A. A.; Tyce, G. M.

In: Medicine and Science in Sports and Exercise, Vol. 21, No. 5, 1989, p. 558-562.

Research output: Contribution to journalArticle

Bauer, BA, Rogers, PJ, Miller, TD, Bove, AA & Tyce, GM 1989, 'Exercise training produces changes in free and conjugated catecholamines', Medicine and Science in Sports and Exercise, vol. 21, no. 5, pp. 558-562.
Bauer, Brent A ; Rogers, P. J. ; Miller, T. D. ; Bove, A. A. ; Tyce, G. M. / Exercise training produces changes in free and conjugated catecholamines. In: Medicine and Science in Sports and Exercise. 1989 ; Vol. 21, No. 5. pp. 558-562.
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