Evolving role of revascularization in older adults with acute coronary syndrome

Shahyar Gharacholou, Karen P. Alexander

Research output: Contribution to journalArticle

Abstract

Revascularization following acute coronary syndrome reduces morbidity and, in some cases, improves survival. Revascularization is part of a care plan that must include optimal medical therapy for secondary prevention and also counseling to promote healthy behaviors. The use of revascularization and guideline-recommended therapies declines as patients age, which may be attributed, in part, to geriatric or "age-associated" vulnerability. Such common geriatric factors include functional decline, comorbid illness, heightened risks of adverse procedural complications or adverse drug reactions, and clinician-perceived decisions regarding risk versus benefit. Patient selection for invasive management must consider patient preferences and risks from age-related multimorbidity. In selected older adults for whom revascularization is favored, advances in percutaneous coronary practices have paralleled improvements in cardiac surgery, both of which are employed to treat older adults in the setting of acute ischemic heart disease.

Original languageEnglish (US)
Pages (from-to)355-365
Number of pages11
JournalCurrent Cardiovascular Risk Reports
Volume3
Issue number5
DOIs
StatePublished - Dec 1 2009
Externally publishedYes

Fingerprint

Acute Coronary Syndrome
Geriatrics
Patient Preference
Secondary Prevention
Drug-Related Side Effects and Adverse Reactions
Patient Selection
Thoracic Surgery
Myocardial Ischemia
Comorbidity
Counseling
Guidelines
Morbidity
Survival
Therapeutics

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

Cite this

Evolving role of revascularization in older adults with acute coronary syndrome. / Gharacholou, Shahyar; Alexander, Karen P.

In: Current Cardiovascular Risk Reports, Vol. 3, No. 5, 01.12.2009, p. 355-365.

Research output: Contribution to journalArticle

@article{c74a0fb47fc64f97945d17b5ef755a42,
title = "Evolving role of revascularization in older adults with acute coronary syndrome",
abstract = "Revascularization following acute coronary syndrome reduces morbidity and, in some cases, improves survival. Revascularization is part of a care plan that must include optimal medical therapy for secondary prevention and also counseling to promote healthy behaviors. The use of revascularization and guideline-recommended therapies declines as patients age, which may be attributed, in part, to geriatric or {"}age-associated{"} vulnerability. Such common geriatric factors include functional decline, comorbid illness, heightened risks of adverse procedural complications or adverse drug reactions, and clinician-perceived decisions regarding risk versus benefit. Patient selection for invasive management must consider patient preferences and risks from age-related multimorbidity. In selected older adults for whom revascularization is favored, advances in percutaneous coronary practices have paralleled improvements in cardiac surgery, both of which are employed to treat older adults in the setting of acute ischemic heart disease.",
author = "Shahyar Gharacholou and Alexander, {Karen P.}",
year = "2009",
month = "12",
day = "1",
doi = "10.1007/s12170-009-0052-5",
language = "English (US)",
volume = "3",
pages = "355--365",
journal = "Current Cardiovascular Risk Reports",
issn = "1932-9520",
publisher = "Current Medicine Group",
number = "5",

}

TY - JOUR

T1 - Evolving role of revascularization in older adults with acute coronary syndrome

AU - Gharacholou, Shahyar

AU - Alexander, Karen P.

PY - 2009/12/1

Y1 - 2009/12/1

N2 - Revascularization following acute coronary syndrome reduces morbidity and, in some cases, improves survival. Revascularization is part of a care plan that must include optimal medical therapy for secondary prevention and also counseling to promote healthy behaviors. The use of revascularization and guideline-recommended therapies declines as patients age, which may be attributed, in part, to geriatric or "age-associated" vulnerability. Such common geriatric factors include functional decline, comorbid illness, heightened risks of adverse procedural complications or adverse drug reactions, and clinician-perceived decisions regarding risk versus benefit. Patient selection for invasive management must consider patient preferences and risks from age-related multimorbidity. In selected older adults for whom revascularization is favored, advances in percutaneous coronary practices have paralleled improvements in cardiac surgery, both of which are employed to treat older adults in the setting of acute ischemic heart disease.

AB - Revascularization following acute coronary syndrome reduces morbidity and, in some cases, improves survival. Revascularization is part of a care plan that must include optimal medical therapy for secondary prevention and also counseling to promote healthy behaviors. The use of revascularization and guideline-recommended therapies declines as patients age, which may be attributed, in part, to geriatric or "age-associated" vulnerability. Such common geriatric factors include functional decline, comorbid illness, heightened risks of adverse procedural complications or adverse drug reactions, and clinician-perceived decisions regarding risk versus benefit. Patient selection for invasive management must consider patient preferences and risks from age-related multimorbidity. In selected older adults for whom revascularization is favored, advances in percutaneous coronary practices have paralleled improvements in cardiac surgery, both of which are employed to treat older adults in the setting of acute ischemic heart disease.

UR - http://www.scopus.com/inward/record.url?scp=84873507538&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84873507538&partnerID=8YFLogxK

U2 - 10.1007/s12170-009-0052-5

DO - 10.1007/s12170-009-0052-5

M3 - Article

AN - SCOPUS:84873507538

VL - 3

SP - 355

EP - 365

JO - Current Cardiovascular Risk Reports

JF - Current Cardiovascular Risk Reports

SN - 1932-9520

IS - 5

ER -