Evolution of Hematopoietic Cell Transplantation for Immunoglobulin Light Chain Amyloidosis

Taimur Sher; Angela Dispenzieri; Morie A. Gertz

doi:10.1016/j.bbmt.2015.10.010

Evolution of Hematopoietic Cell Transplantation for Immunoglobulin Light Chain Amyloidosis

Taimur Sher, Angela Dispenzieri, Morie A. Gertz

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Abstract

Immunoglobulin light chain amyloidosis is the most common type of systemic amyloidosis. Hematopoietic stem cell transplantation (HCT) is an effective treatment option for AL however due to multi-organ involvement in this disease HCT is feasible in a minority of patients. To maximize the benefit and minimize toxicity it is of paramount importance to optimize the selection of patients for HCT. In this review we discuss evolution of HCT and its typical application to a case of AL amyloidosis.

Original language	English (US)
Pages (from-to)	796-801
Number of pages	6
Journal	Biology of Blood and Marrow Transplantation
Volume	22
Issue number	5
DOIs	https://doi.org/10.1016/j.bbmt.2015.10.010
State	Published - May 1 2016

Keywords

AL amyloidosis
Hematopoeitic stem cell transplantation
Immunoglobulin light chain amyloidosis
Stem cell transplantation

ASJC Scopus subject areas

Hematology
Transplantation

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10.1016/j.bbmt.2015.10.010

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title = "Evolution of Hematopoietic Cell Transplantation for Immunoglobulin Light Chain Amyloidosis",

abstract = "Immunoglobulin light chain amyloidosis is the most common type of systemic amyloidosis. Hematopoietic stem cell transplantation (HCT) is an effective treatment option for AL however due to multi-organ involvement in this disease HCT is feasible in a minority of patients. To maximize the benefit and minimize toxicity it is of paramount importance to optimize the selection of patients for HCT. In this review we discuss evolution of HCT and its typical application to a case of AL amyloidosis.",

keywords = "AL amyloidosis, Hematopoeitic stem cell transplantation, Immunoglobulin light chain amyloidosis, Stem cell transplantation",

author = "Taimur Sher and Angela Dispenzieri and Gertz, {Morie A.}",

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AU - Dispenzieri, Angela

AU - Gertz, Morie A.

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Y1 - 2016/5/1

N2 - Immunoglobulin light chain amyloidosis is the most common type of systemic amyloidosis. Hematopoietic stem cell transplantation (HCT) is an effective treatment option for AL however due to multi-organ involvement in this disease HCT is feasible in a minority of patients. To maximize the benefit and minimize toxicity it is of paramount importance to optimize the selection of patients for HCT. In this review we discuss evolution of HCT and its typical application to a case of AL amyloidosis.

AB - Immunoglobulin light chain amyloidosis is the most common type of systemic amyloidosis. Hematopoietic stem cell transplantation (HCT) is an effective treatment option for AL however due to multi-organ involvement in this disease HCT is feasible in a minority of patients. To maximize the benefit and minimize toxicity it is of paramount importance to optimize the selection of patients for HCT. In this review we discuss evolution of HCT and its typical application to a case of AL amyloidosis.

KW - AL amyloidosis

KW - Hematopoeitic stem cell transplantation

KW - Immunoglobulin light chain amyloidosis

KW - Stem cell transplantation

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Evolution of Hematopoietic Cell Transplantation for Immunoglobulin Light Chain Amyloidosis

Abstract

Keywords

ASJC Scopus subject areas

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