Evidence of cardiac ischemia during seizures in drug refractory epilepsy patients

Simona Tigaran, H. Mølgaard, R. McClelland, M. Dam, A. S. Jaffe

Research output: Contribution to journalArticle

121 Scopus citations


The authors investigated whether patients with drug refractory epilepsy have cardiovascular abnormalities that might be related to a high frequency of sudden death. Twenty-three subjects underwent comprehensive cardiovascular evaluations before and during video-EEG monitoring. ST-segment depression occurred in 40% and was associated with a higher maximum heart rate during seizures. These data suggest that cardiac ischemia may occur in these patients.

Original languageEnglish (US)
Pages (from-to)492-495
Number of pages4
Issue number3
StatePublished - Feb 11 2003


ASJC Scopus subject areas

  • Clinical Neurology

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