Evidence for genetic heterogeneity in hereditary neuralgic amyotrophy

G. D.J. Watts; K. C. O'Briant; T. E. Borreson; A. J. Windebank; Phillip F. Chance

doi:10.1212/WNL.56.5.675

Evidence for genetic heterogeneity in hereditary neuralgic amyotrophy

G. D.J. Watts, K. C. O'Briant, T. E. Borreson, A. J. Windebank, Phillip F. Chance

Neurology

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

Hereditary neuralgic amyotrophy (HNA) is a rare autosoreal dominant disorder characterized by recurrent episodes of severe arm and shoulder pain with weakness, atrophy, and sensory impairment in a brachial plexus distribution. Recent studies mapped the HNA locus to chromosome 17q25. Two pedigrees with clinically typical HNA in which markers from chromosome 17q25 do not cosegregate with the disease and in which lod scores do not support linkage to chromosome 17q25 were identified.

Original language	English (US)
Pages (from-to)	675-678
Number of pages	4
Journal	Neurology
Volume	56
Issue number	5
DOIs	https://doi.org/10.1212/WNL.56.5.675
State	Published - Mar 13 2001

ASJC Scopus subject areas

Clinical Neurology

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abstract = "Hereditary neuralgic amyotrophy (HNA) is a rare autosoreal dominant disorder characterized by recurrent episodes of severe arm and shoulder pain with weakness, atrophy, and sensory impairment in a brachial plexus distribution. Recent studies mapped the HNA locus to chromosome 17q25. Two pedigrees with clinically typical HNA in which markers from chromosome 17q25 do not cosegregate with the disease and in which lod scores do not support linkage to chromosome 17q25 were identified.",

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AU - Windebank, A. J.

AU - Chance, Phillip F.

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AB - Hereditary neuralgic amyotrophy (HNA) is a rare autosoreal dominant disorder characterized by recurrent episodes of severe arm and shoulder pain with weakness, atrophy, and sensory impairment in a brachial plexus distribution. Recent studies mapped the HNA locus to chromosome 17q25. Two pedigrees with clinically typical HNA in which markers from chromosome 17q25 do not cosegregate with the disease and in which lod scores do not support linkage to chromosome 17q25 were identified.

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Evidence for genetic heterogeneity in hereditary neuralgic amyotrophy

Abstract

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