Abstract
Hereditary neuralgic amyotrophy (HNA) is a rare autosoreal dominant disorder characterized by recurrent episodes of severe arm and shoulder pain with weakness, atrophy, and sensory impairment in a brachial plexus distribution. Recent studies mapped the HNA locus to chromosome 17q25. Two pedigrees with clinically typical HNA in which markers from chromosome 17q25 do not cosegregate with the disease and in which lod scores do not support linkage to chromosome 17q25 were identified.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 675-678 |
| Number of pages | 4 |
| Journal | Neurology |
| Volume | 56 |
| Issue number | 5 |
| State | Published - Mar 13 2001 |
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ASJC Scopus subject areas
- Neuroscience(all)
Cite this
Evidence for genetic heterogeneity in hereditary neuralgic amyotrophy. / Watts, G. D J; O'Briant, K. C.; Borreson, T. E.; Windebank, Anthony John; Chance, Phillip F.
In: Neurology, Vol. 56, No. 5, 13.03.2001, p. 675-678.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Evidence for genetic heterogeneity in hereditary neuralgic amyotrophy
AU - Watts, G. D J
AU - O'Briant, K. C.
AU - Borreson, T. E.
AU - Windebank, Anthony John
AU - Chance, Phillip F.
PY - 2001/3/13
Y1 - 2001/3/13
N2 - Hereditary neuralgic amyotrophy (HNA) is a rare autosoreal dominant disorder characterized by recurrent episodes of severe arm and shoulder pain with weakness, atrophy, and sensory impairment in a brachial plexus distribution. Recent studies mapped the HNA locus to chromosome 17q25. Two pedigrees with clinically typical HNA in which markers from chromosome 17q25 do not cosegregate with the disease and in which lod scores do not support linkage to chromosome 17q25 were identified.
AB - Hereditary neuralgic amyotrophy (HNA) is a rare autosoreal dominant disorder characterized by recurrent episodes of severe arm and shoulder pain with weakness, atrophy, and sensory impairment in a brachial plexus distribution. Recent studies mapped the HNA locus to chromosome 17q25. Two pedigrees with clinically typical HNA in which markers from chromosome 17q25 do not cosegregate with the disease and in which lod scores do not support linkage to chromosome 17q25 were identified.
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UR - http://www.scopus.com/inward/citedby.url?scp=0035852962&partnerID=8YFLogxK
M3 - Article
C2 - 11245726
AN - SCOPUS:0035852962
VL - 56
SP - 675
EP - 678
JO - Neurology
JF - Neurology
SN - 0028-3878
IS - 5
ER -