Abstract
The substantial increase of randomized controlled trials demand familiarity with the essential aspects of their design and performance by the cardiologist, particularly the adequate interpretation and applicability of the results. In this clinically-based review, we discuss some important aspects in the assessment of novel contemporary therapy such as the use and analysis of composite endpoints; implications from early termination of trials and extrapolation of results to the population.
Translated title of the contribution | Evidence-based cardiology: Practical applications from epidemiology I. the evaluation of a novel drug or therapy |
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Original language | Spanish |
Pages (from-to) | 47-52 |
Number of pages | 6 |
Journal | Archivos de Cardiologia de Mexico |
Volume | 81 |
Issue number | 1 |
State | Published - Dec 1 2011 |
Keywords
- Critical analysis
- Novel therapy
- Randomized controlled trial
- Usa
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine