Evaluation of vibro-acoustography techniques to map absorbed dose distribution in irradiated phantoms

Silvio L. Vieira, Randall R. Kinnick, André L. Baggio, Patricia Nicolucci, Mostafa Fatemi, Adilton O. Carneiro

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This work presents Vibro-acoustography (VA) as a tool to visualize absorbed dose distributions in a polymer gel dosimeter. VA uses the radiation force of focused ultrasound to vibrate a small region of the sample. Different modalities of VA were used to investigate the feasibility of this technique to evaluate dose distribution in irradiated 'MAGIC' polymer gel. A phantom was designed using this polymer with 2% w/w added glass microspheres having an average diameter range between 40-75 μm. The phantom was irradiated using conventional 10 MeV X-rays from a linear accelerator at a distance of 100 cm. An absorbed dose of 50 gray was delivered to the gel. To study the phenomena of dose distribution, continuous wave (CW), toneburst and multifrequency VA were applied to the phantom. Images were generated from the phase and magnitude of the emitted sound from the irradiated area. The comparative accuracy of the different VA results were validated using transverse relaxation rate (R2) image analysis by Magnetic Resonance Imaging (MRI) and a treatment planning system. A contour map of R2 was registered with the transverse CW images, obtained with the focal point on the top surface, and a good correlation was found between the images. The axial profile of irradiated inclusion from the toneburst VA image obtained with excitation frequency of 75 kHz showed the best accuracy compared to other VA modalities. The results show that VA imaging has potential to visualize dose distribution in a polymer gel dosimeter.

Original languageEnglish (US)
Title of host publicationProceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
Pages796-799
Number of pages4
DOIs
StatePublished - 2009
Event31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 - Minneapolis, MN, United States
Duration: Sep 2 2009Sep 6 2009

Other

Other31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
CountryUnited States
CityMinneapolis, MN
Period9/2/099/6/09

Fingerprint

Elasticity Imaging Techniques
Gels
Dosimetry
Dosimeters
Polymers
Linear accelerators
Microspheres
Image analysis
Ultrasonics
Acoustic waves
Imaging techniques
Radiation
Planning
X rays
Glass
Particle Accelerators
Magnetic Resonance Imaging
X-Rays

ASJC Scopus subject areas

  • Cell Biology
  • Developmental Biology
  • Biomedical Engineering
  • Medicine(all)

Cite this

Vieira, S. L., Kinnick, R. R., Baggio, A. L., Nicolucci, P., Fatemi, M., & Carneiro, A. O. (2009). Evaluation of vibro-acoustography techniques to map absorbed dose distribution in irradiated phantoms. In Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 (pp. 796-799). [5333608] https://doi.org/10.1109/IEMBS.2009.5333608

Evaluation of vibro-acoustography techniques to map absorbed dose distribution in irradiated phantoms. / Vieira, Silvio L.; Kinnick, Randall R.; Baggio, André L.; Nicolucci, Patricia; Fatemi, Mostafa; Carneiro, Adilton O.

Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009. 2009. p. 796-799 5333608.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Vieira, SL, Kinnick, RR, Baggio, AL, Nicolucci, P, Fatemi, M & Carneiro, AO 2009, Evaluation of vibro-acoustography techniques to map absorbed dose distribution in irradiated phantoms. in Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009., 5333608, pp. 796-799, 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009, Minneapolis, MN, United States, 9/2/09. https://doi.org/10.1109/IEMBS.2009.5333608
Vieira SL, Kinnick RR, Baggio AL, Nicolucci P, Fatemi M, Carneiro AO. Evaluation of vibro-acoustography techniques to map absorbed dose distribution in irradiated phantoms. In Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009. 2009. p. 796-799. 5333608 https://doi.org/10.1109/IEMBS.2009.5333608
Vieira, Silvio L. ; Kinnick, Randall R. ; Baggio, André L. ; Nicolucci, Patricia ; Fatemi, Mostafa ; Carneiro, Adilton O. / Evaluation of vibro-acoustography techniques to map absorbed dose distribution in irradiated phantoms. Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009. 2009. pp. 796-799
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