Evaluation of the material properties of the subsynovial connective tissue in carpal tunnel syndrome

Naoki Osamura, Chunfeng D Zhao, Mark E. Zobitz, Kai N. An, Peter C Amadio

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

Background: The purpose of this study was to determine the material properties of the normal carpal tunnel subsynovial connective tissue in response to shear stress. Methods: The shear modulus and maximum shear strength were measured with a custom-made micro-tester in 10 specimens of subsynovial connective tissue from 10 wrists in eight patients with idiopathic carpal tunnel syndrome and in 10 specimens from five fresh frozen cadavers without a history of carpal tunnel syndrome. Findings: The mean shear modulus was 22.8 (SD 15.4) kPa for the patient group and 2.7 (SD 1.8) kPa for the control group. The mean maximum shear strength was 54.6 (SD 20.3) kPa for the patient group and 23.3 (SD 10.7) kPa for the control group. The values for the patient group were significantly higher than the control group (P < 0.05). Interpretation: The material properties of subsynovial connective tissue are altered in patients with idiopathic carpal tunnel syndrome. The impact, if any, of these altered properties on carpal tunnel syndrome remains to be elucidated.

Original languageEnglish (US)
Pages (from-to)999-1003
Number of pages5
JournalClinical Biomechanics
Volume22
Issue number9
DOIs
StatePublished - Nov 2007

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Carpal Tunnel Syndrome
Connective Tissue
Shear Strength
Wrist
Control Groups
Cadaver

Keywords

  • Biomechanics
  • Carpal tunnel syndrome
  • Shear stress
  • Subsynovial connective tissue

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

Cite this

Evaluation of the material properties of the subsynovial connective tissue in carpal tunnel syndrome. / Osamura, Naoki; Zhao, Chunfeng D; Zobitz, Mark E.; An, Kai N.; Amadio, Peter C.

In: Clinical Biomechanics, Vol. 22, No. 9, 11.2007, p. 999-1003.

Research output: Contribution to journalArticle

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