Evaluation of patients with minimally obstructive coronary artery disease and angina

David Hasdai, Charles R. Cannan, Verghese Mathew, David Holmes, Amir Lerman

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Atherosclerotic coronary artery disease is a progressive process adversely affecting the integrity of the coronary vasculature. In past years, most studies have focused on the morphological changes leading to compromised coronary blood flow in atherosclerosis. However, in recent years it has become apparent that abnormal coronary vasomotor regulation may precede or accompany gross morphological changes in coronary atherosclerotic disease. In fact, the pathophysiology of angina pectoris in many patients with risk factors for atherosclerosis and minimally obstructive disease may involve abnormal coronary vasomotor tone regulation. The aim of the present article is to describe a clinical approach to patients with angina pectoris and minimally obstructive coronary artery disease based on current knowledge of coronary vasomotor regulation.

Original languageEnglish (US)
Pages (from-to)203-208
Number of pages6
JournalInternational Journal of Cardiology
Volume53
Issue number3
DOIs
StatePublished - Mar 1996

Fingerprint

Angina Pectoris
Coronary Artery Disease
Atherosclerosis
Coronary Disease

Keywords

  • Acetylcholine
  • Adenosine
  • Angina pectoris
  • Atherosclerosis
  • Coronary artery disease
  • Doppler
  • Endothelium

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Evaluation of patients with minimally obstructive coronary artery disease and angina. / Hasdai, David; Cannan, Charles R.; Mathew, Verghese; Holmes, David; Lerman, Amir.

In: International Journal of Cardiology, Vol. 53, No. 3, 03.1996, p. 203-208.

Research output: Contribution to journalArticle

Hasdai, David ; Cannan, Charles R. ; Mathew, Verghese ; Holmes, David ; Lerman, Amir. / Evaluation of patients with minimally obstructive coronary artery disease and angina. In: International Journal of Cardiology. 1996 ; Vol. 53, No. 3. pp. 203-208.
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