Evaluation of a screening tool for bleeding disorders in a US multisite cohort of women with menorrhagia

Claire S. Philipp, Ambarina Faiz, John A. Heit, Peter A. Kouides, Andrea Lukes, Sidney F. Stein, Vanessa Byams, Connie H. Miller, Roshni Kulkarni

Research output: Contribution to journalArticlepeer-review

30 Scopus citations

Abstract

Objective The purpose of this study was to determine the usefulness of a simple screening tool for bleeding disorders in a multisite population of women with menorrhagia. Study Design Women with menorrhagia between the ages of 18 and 50 years from 6 geographically diverse US centers underwent hemostatic testing for bleeding disorders, complete blood cell count, and ferritin. A questionnaire that contained all elements of the 8-question screening tool was administered. Sensitivity of the screening tool, a screening tool with a pictorial blood assessment chart (PBAC) score of >185, and a screening tool with serum ferritin were calculated for hemostatic disorders. Results Two hundred and seventeen women who were identified with a PBAC score of <100 participated in the study. The sensitivity of the screening tool was 89% for hemostatic defects, and sensitivity increased to 93% and 95% with a serum ferritin level of ≤20 ng/mL and a PBAC score of >185, respectively. Conclusion This study confirms the usefulness of a short screening tool for the stratification of women with menorrhagia for hemostatic evaluation.

Original languageEnglish (US)
Pages (from-to)209.e1-209.e7
JournalAmerican journal of obstetrics and gynecology
Volume204
Issue number3
DOIs
StatePublished - Mar 2011

Keywords

  • bleeding disorder
  • ferritin
  • hemostatic evaluation
  • menorrhagia

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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