Evaluation of a screening tool for bleeding disorders in a US multisite cohort of women with menorrhagia

Claire S. Philipp; Ambarina Faiz; John A. Heit; Peter A. Kouides; Andrea Lukes; Sidney F. Stein; Vanessa Byams; Connie H. Miller; Roshni Kulkarni

doi:10.1016/j.ajog.2010.10.897

Evaluation of a screening tool for bleeding disorders in a US multisite cohort of women with menorrhagia

Claire S. Philipp, Ambarina Faiz, John A. Heit, Peter A. Kouides, Andrea Lukes, Sidney F. Stein, Vanessa Byams, Connie H. Miller, Roshni Kulkarni

Cardiovascular Medicine

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

Objective The purpose of this study was to determine the usefulness of a simple screening tool for bleeding disorders in a multisite population of women with menorrhagia. Study Design Women with menorrhagia between the ages of 18 and 50 years from 6 geographically diverse US centers underwent hemostatic testing for bleeding disorders, complete blood cell count, and ferritin. A questionnaire that contained all elements of the 8-question screening tool was administered. Sensitivity of the screening tool, a screening tool with a pictorial blood assessment chart (PBAC) score of >185, and a screening tool with serum ferritin were calculated for hemostatic disorders. Results Two hundred and seventeen women who were identified with a PBAC score of <100 participated in the study. The sensitivity of the screening tool was 89% for hemostatic defects, and sensitivity increased to 93% and 95% with a serum ferritin level of ≤20 ng/mL and a PBAC score of >185, respectively. Conclusion This study confirms the usefulness of a short screening tool for the stratification of women with menorrhagia for hemostatic evaluation.

Original language	English (US)
Pages (from-to)	209.e1-209.e7
Journal	American journal of obstetrics and gynecology
Volume	204
Issue number	3
DOIs	https://doi.org/10.1016/j.ajog.2010.10.897
State	Published - Mar 2011

Keywords

bleeding disorder
ferritin
hemostatic evaluation
menorrhagia

ASJC Scopus subject areas

Obstetrics and Gynecology

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10.1016/j.ajog.2010.10.897

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title = "Evaluation of a screening tool for bleeding disorders in a US multisite cohort of women with menorrhagia",

abstract = "Objective The purpose of this study was to determine the usefulness of a simple screening tool for bleeding disorders in a multisite population of women with menorrhagia. Study Design Women with menorrhagia between the ages of 18 and 50 years from 6 geographically diverse US centers underwent hemostatic testing for bleeding disorders, complete blood cell count, and ferritin. A questionnaire that contained all elements of the 8-question screening tool was administered. Sensitivity of the screening tool, a screening tool with a pictorial blood assessment chart (PBAC) score of >185, and a screening tool with serum ferritin were calculated for hemostatic disorders. Results Two hundred and seventeen women who were identified with a PBAC score of <100 participated in the study. The sensitivity of the screening tool was 89% for hemostatic defects, and sensitivity increased to 93% and 95% with a serum ferritin level of ≤20 ng/mL and a PBAC score of >185, respectively. Conclusion This study confirms the usefulness of a short screening tool for the stratification of women with menorrhagia for hemostatic evaluation.",

keywords = "bleeding disorder, ferritin, hemostatic evaluation, menorrhagia",

author = "Philipp, {Claire S.} and Ambarina Faiz and Heit, {John A.} and Kouides, {Peter A.} and Andrea Lukes and Stein, {Sidney F.} and Vanessa Byams and Miller, {Connie H.} and Roshni Kulkarni",

note = "Funding Information: Supported by the Association of Teachers of Preventive Medicine/Centers for Disease Control and Prevention (C.S.P., J.A.H., P.A.K., A.L., RK, and S.F.S.). ",

year = "2011",

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doi = "10.1016/j.ajog.2010.10.897",

language = "English (US)",

volume = "204",

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T1 - Evaluation of a screening tool for bleeding disorders in a US multisite cohort of women with menorrhagia

AU - Philipp, Claire S.

AU - Faiz, Ambarina

AU - Heit, John A.

AU - Kouides, Peter A.

AU - Lukes, Andrea

AU - Stein, Sidney F.

AU - Byams, Vanessa

AU - Miller, Connie H.

AU - Kulkarni, Roshni

N1 - Funding Information: Supported by the Association of Teachers of Preventive Medicine/Centers for Disease Control and Prevention (C.S.P., J.A.H., P.A.K., A.L., RK, and S.F.S.).

PY - 2011/3

Y1 - 2011/3

N2 - Objective The purpose of this study was to determine the usefulness of a simple screening tool for bleeding disorders in a multisite population of women with menorrhagia. Study Design Women with menorrhagia between the ages of 18 and 50 years from 6 geographically diverse US centers underwent hemostatic testing for bleeding disorders, complete blood cell count, and ferritin. A questionnaire that contained all elements of the 8-question screening tool was administered. Sensitivity of the screening tool, a screening tool with a pictorial blood assessment chart (PBAC) score of >185, and a screening tool with serum ferritin were calculated for hemostatic disorders. Results Two hundred and seventeen women who were identified with a PBAC score of <100 participated in the study. The sensitivity of the screening tool was 89% for hemostatic defects, and sensitivity increased to 93% and 95% with a serum ferritin level of ≤20 ng/mL and a PBAC score of >185, respectively. Conclusion This study confirms the usefulness of a short screening tool for the stratification of women with menorrhagia for hemostatic evaluation.

AB - Objective The purpose of this study was to determine the usefulness of a simple screening tool for bleeding disorders in a multisite population of women with menorrhagia. Study Design Women with menorrhagia between the ages of 18 and 50 years from 6 geographically diverse US centers underwent hemostatic testing for bleeding disorders, complete blood cell count, and ferritin. A questionnaire that contained all elements of the 8-question screening tool was administered. Sensitivity of the screening tool, a screening tool with a pictorial blood assessment chart (PBAC) score of >185, and a screening tool with serum ferritin were calculated for hemostatic disorders. Results Two hundred and seventeen women who were identified with a PBAC score of <100 participated in the study. The sensitivity of the screening tool was 89% for hemostatic defects, and sensitivity increased to 93% and 95% with a serum ferritin level of ≤20 ng/mL and a PBAC score of >185, respectively. Conclusion This study confirms the usefulness of a short screening tool for the stratification of women with menorrhagia for hemostatic evaluation.

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KW - hemostatic evaluation

KW - menorrhagia

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Evaluation of a screening tool for bleeding disorders in a US multisite cohort of women with menorrhagia

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