Evaluation and treatment of thrombocytopenia in the neonatal intensive care unit

Martha C. Sola, Antonio Del Vecchio, Lisa M. Rimsza

Research output: Contribution to journalArticle

70 Scopus citations

Abstract

Thrombocytopenia is a very frequent problem among sick neonates, affecting up to 35% of all infants admitted to the NICU. Although multiple clinical conditions have been causally associated with neonatal thrombocytopenia, the cause of the thrombocytopenia is unclear in up to 60% of affected neonates. This article provides neonatologists with a practical approach to the thrombocytopenic neonate, with an emphasis on conditions that could be life-threatening or could have significant implications for further pregnancies. An overview of the current therapeutic modalities is also presented, including a discussion of the possible use of recombinant thrombopoietic cytokines to treat certain groups of thrombocytopenic neonates.

Original languageEnglish (US)
Pages (from-to)655-679
Number of pages25
JournalClinics in Perinatology
Volume27
Issue number3
DOIs
StatePublished - Jan 1 2000

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

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